GLGA_PROM9
ID GLGA_PROM9 Reviewed; 483 AA.
AC Q31BS5;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN OrderedLocusNames=PMT9312_0609;
OS Prochlorococcus marinus (strain MIT 9312).
OC Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC Prochlorococcus.
OX NCBI_TaxID=74546;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 9312;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F.,
RA Land M., Kyrpides N., Lykidis A., Richardson P.;
RT "Complete sequence of Prochlorococcus marinus str. MIT 9312.";
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000111; ABB49670.1; -; Genomic_DNA.
DR RefSeq; WP_011376165.1; NC_007577.1.
DR AlphaFoldDB; Q31BS5; -.
DR SMR; Q31BS5; -.
DR STRING; 74546.PMT9312_0609; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABB49670; ABB49670; PMT9312_0609.
DR KEGG; pmi:PMT9312_0609; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_3; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000002715; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..483
FT /note="Glycogen synthase"
FT /id="PRO_0000230254"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 483 AA; 55037 MW; 73EFD58025E9B281 CRC64;
MRILLAAAEC APMIKVGGMG DVVGSLPPSL IKLGHDVRVI IPGYGKLWSL LEVSNEPVFR
ANTMGTDFAV YEAKHPIHNY VIYLVGHPIF DSDQIYGGEN EDWRFTFFAS ATSEFAWNCW
KPQVLHCHDW HTGMIPVWMH QDPEISTVFT IHNLKYQGPW RWKLEKMTWC PWYMHGDHTM
AAAMLYADRV NAVSPTYADE IKTHEYGESL EGLLNYISGK LRGILNGIDL DEWNPAKDPV
LPAKFSINNL KNRTENKKIL QREMGLEVNP KKYLLGMVSR LVDQKGVDLL LQVSRRLLAY
TDSQIAVLGT GDRYLESGLW QLALDYPGRF SVFLTYDDSL SRLIYGGSDA FLMPSRFEPC
GISQLLAMRY GSVPIVRRVG GLVDTVLPHD PENNSGTGFC FDRFEPIDFY TSLVRSWEAF
RHKDSWELLQ KRAMSQEFSW QRSALEYEMM YKDVCGIKEP SPDVAEVEKF SYGQSADPSL
KKG
