GLGA_PSEA7
ID GLGA_PSEA7 Reviewed; 513 AA.
AC A6V616;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=PSPA7_3141;
OS Pseudomonas aeruginosa (strain PA7).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=381754;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PA7;
RA Dodson R.J., Harkins D., Paulsen I.T.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000744; ABR84969.1; -; Genomic_DNA.
DR RefSeq; WP_012075900.1; NC_009656.1.
DR AlphaFoldDB; A6V616; -.
DR SMR; A6V616; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABR84969; ABR84969; PSPA7_3141.
DR KEGG; pap:PSPA7_3141; -.
DR HOGENOM; CLU_009583_18_4_6; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001582; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..513
FT /note="Glycogen synthase"
FT /id="PRO_1000014378"
FT BINDING 47
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 513 AA; 56351 MW; 22BE64EDEE4C4674 CRC64;
MGHSVAGVCL EEPAVLTAFP SLLHPQDPPQ QRDRILFVTA ELSDFVKVGG LGDFSAALPR
VLRRQHAVRV LLPGYRQVLE RCSDLRILGS LPGRAAIPPC EIGLVTLDDG LEVMLVLCPL
LYEREGTPYM DDQGNDWADN HLRFARLCLA AAEIAGGHGA QGWQPGLVHA NDWPSALTPA
YMAWNGVRTP SLFTIHNLAY QGLCDLQCSA ELGLPDEALS PESMEFHGRL SFLKAGIAHA
HHITTVSETY AQEITTPEYG CGLHGILKCK VEKRQLSGIV NGIDDSWQPH CDPHLVAGFS
ARQWAGKRAN TRYVEERFGL EPGKGPLFAV VSRLVQQKGI DLTLEISDAL LQAGGRLVSI
GRGEPSLEKA MLDLSRRHPG QVGVHIGFDE TDARRIYAGS DFLLMPSRYE PCGLSQLYAQ
CFGSLPIARC TGGLADTIVD GVTGFLFREE TAQSYLDAVL RAINVYHCPA LLNAMRCKAM
AAPMFWRDSV EPYNRLYRRL LRNTAPAWRG VRP