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GLGA_PSEA7
ID   GLGA_PSEA7              Reviewed;         513 AA.
AC   A6V616;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=PSPA7_3141;
OS   Pseudomonas aeruginosa (strain PA7).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=381754;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PA7;
RA   Dodson R.J., Harkins D., Paulsen I.T.;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; CP000744; ABR84969.1; -; Genomic_DNA.
DR   RefSeq; WP_012075900.1; NC_009656.1.
DR   AlphaFoldDB; A6V616; -.
DR   SMR; A6V616; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; ABR84969; ABR84969; PSPA7_3141.
DR   KEGG; pap:PSPA7_3141; -.
DR   HOGENOM; CLU_009583_18_4_6; -.
DR   OMA; TWCPWYM; -.
DR   OrthoDB; 83240at2; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000001582; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT   CHAIN           1..513
FT                   /note="Glycogen synthase"
FT                   /id="PRO_1000014378"
FT   BINDING         47
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   513 AA;  56351 MW;  22BE64EDEE4C4674 CRC64;
     MGHSVAGVCL EEPAVLTAFP SLLHPQDPPQ QRDRILFVTA ELSDFVKVGG LGDFSAALPR
     VLRRQHAVRV LLPGYRQVLE RCSDLRILGS LPGRAAIPPC EIGLVTLDDG LEVMLVLCPL
     LYEREGTPYM DDQGNDWADN HLRFARLCLA AAEIAGGHGA QGWQPGLVHA NDWPSALTPA
     YMAWNGVRTP SLFTIHNLAY QGLCDLQCSA ELGLPDEALS PESMEFHGRL SFLKAGIAHA
     HHITTVSETY AQEITTPEYG CGLHGILKCK VEKRQLSGIV NGIDDSWQPH CDPHLVAGFS
     ARQWAGKRAN TRYVEERFGL EPGKGPLFAV VSRLVQQKGI DLTLEISDAL LQAGGRLVSI
     GRGEPSLEKA MLDLSRRHPG QVGVHIGFDE TDARRIYAGS DFLLMPSRYE PCGLSQLYAQ
     CFGSLPIARC TGGLADTIVD GVTGFLFREE TAQSYLDAVL RAINVYHCPA LLNAMRCKAM
     AAPMFWRDSV EPYNRLYRRL LRNTAPAWRG VRP
 
 
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