ID   GLGA_PSEPF              Reviewed;         487 AA.
AC   Q3KD65;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 2.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Pfl01_2549;
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pf0-1;
RX   PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA   Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA   Jackson R.W., Preston G.M., Zhang X.-X., Moon C.D., Gehrig S.M.,
RA   Godfrey S.A.C., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA   Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA   Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA   Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA   Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT   "Genomic and genetic analyses of diversity and plant interactions of
RT   Pseudomonas fluorescens.";
RL   Genome Biol. 10:R51.1-R51.16(2009).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABA74290.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000094; ABA74290.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q3KD65; -.
DR   SMR; Q3KD65; -.
DR   STRING; 205922.Pfl01_2549; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; ABA74290; ABA74290; Pfl01_2549.
DR   KEGG; pfo:Pfl01_2549; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_4_6; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000002704; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT   CHAIN           1..487
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000230257"
FT   BINDING         23
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   487 AA;  53003 MW;  449B966E906E6CB3 CRC64;
     MASQNPNKKK VLFVTSEIAD LVKTGGLGDV SAALPRAMAH LHDVRVLIPG YPQVMNSENP
     IHIIGELGGH AALPPCKIGR MDMPDGLVIY VLICPELYAR DGGPYGANNG RDWPDNHIRF
     ARLGLAAADI AANLAQIHWC PDLVHAHDWP AGLAPAYMHW RGQRTPTLFT IHNLAYQGVT
     SLGSCPELGI PAHALQQEGM EFYGKMSFLK AGMAYSSHIT TVSATYAQEI TTPDFGCGLD
     GFLAAKTQQG LLSGIPNGID ESWDAATDPH LFAPFAIGDW EGKAINAAHV RELFGLKDSE
     GPLFAVVSRL VYQKGLDLTE AVSEYIVQNG GQIAIIGRGE PEEEQAMREL ALRFPGQIGV
     RIGFNETDAR RMFAGSDFLL MPSRYEPCGL SQMYAQRFGS LPVARNTGGL ADTIENGVTG
     FLFNESTADS YREALSRAFK VFAFPELLNA MRCRAMAAPF NWCKAVEPYA ELYEKLVAKA
     LGKTHHK