GLGA_RALSO
ID GLGA_RALSO Reviewed; 541 AA.
AC Q8XT73;
DT 10-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=RSp0242;
GN ORFNames=RS03725;
OS Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OG Plasmid megaplasmid Rsp.
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=267608;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=11823852; DOI=10.1038/415497a;
RA Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL Nature 415:497-502(2002).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; AL646053; CAD17393.1; -; Genomic_DNA.
DR RefSeq; WP_011003556.1; NC_003296.1.
DR AlphaFoldDB; Q8XT73; -.
DR SMR; Q8XT73; -.
DR STRING; 267608.RSp0242; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAD17393; CAD17393; RSp0242.
DR GeneID; 60503179; -.
DR KEGG; rso:RSp0242; -.
DR PATRIC; fig|267608.8.peg.3711; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_4_4; -.
DR OMA; TWCPWYM; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Plasmid; Reference proteome;
KW Transferase.
FT CHAIN 1..541
FT /note="Glycogen synthase"
FT /id="PRO_0000188635"
FT REGION 497..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 17
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 541 AA; 57983 MW; 6CF523CB26649FDB CRC64;
MSLNVLFVAS EAVPLAKTGG LGDMVGACAG ALQRAGLHVT VMLPGYPAAQ AQLRDARVAC
ALPDLPGGPA RVLLGAMPDT GVPVLLLDAP ALFDRPGNPY LDACGEPYAD NALRFAAFSH
AAAHVAGGVP DLPAFDIVQA HDWHAALVPL LVKRAGRPVK TVLTVHNLAF QGNFPPRIAQ
DLGLPPEAVR EAGFFGQFSF LKAGLMWADR ITTVSRTYAR EILTDAFGYG MQDVLRARRH
DLVAILNGID NAVWNPSKDA YLSRPFFAGN LSGKHAAKLQ LQTLLRLPKD AHAPLLALGS
RLTHQKMADV ALQALPQMLE AHPDLQVAVL GCGERRYESA MAALAERHPR RMAAVIGYTE
RNAHMLHAGA DLLLHGSRFE PCGLTPLYAM RYGTVPVASR VGGLVDTIAD RGSPEAALRG
ATGFLFDGET PEAMAGAVAR ALRVFVQPRA WRVLQYNGMT TDFGWSQPAS EYLALYATLA
PRATPMPHLQ HWPMRTLARP ASPPDTAPVG KPARRRRTTA LSTTARAHPV ARAAGREKIR
A