GLGA_RHIE6
ID GLGA_RHIE6 Reviewed; 480 AA.
AC B3Q001;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN OrderedLocusNames=RHECIAT_CH0003864;
OS Rhizobium etli (strain CIAT 652).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=491916;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIAT 652;
RA Gonzalez V., Acosta J.L., Santamaria R.I., Bustos P.,
RA Hernandez-Gonzalez I.L., Fernandez J.L., Diaz R., Flores M., Mora J.,
RA Palacios R., Davila G.;
RT "Genome diversity and DNA divergence of Rhizobium etli.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001074; ACE92801.1; -; Genomic_DNA.
DR RefSeq; WP_012485228.1; NC_010994.1.
DR AlphaFoldDB; B3Q001; -.
DR SMR; B3Q001; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ACE92801; ACE92801; RHECIAT_CH0003864.
DR GeneID; 45959030; -.
DR KEGG; rec:RHECIAT_CH0003864; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_4_5; -.
DR OMA; TWCPWYM; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000008817; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..480
FT /note="Glycogen synthase"
FT /id="PRO_1000126092"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 480 AA; 51950 MW; 103BAC1E80D6BE35 CRC64;
MKVLSVSSEV FPLIKTGGLA DVSGALPIAL KAFGVETKTL LPGYPAVMKV IRDPVVRLEF
ADLLGEKATV LEVEHEGLDL LVLHAPAYYD RPGGPYLDPL GKDYPDNWRR FAALSLAAAE
IAAGLLPGWQ PDLVHTHDWQ AALTSVYMRY YPTPELPSVL TIHNIAFQGQ FGSEIFPGLR
LPGHAFAIDG VEYYGTTGFL KGGLQTAHAI TTVSPTYADE ILTPEFGMGL EGVIATRIDN
LHGIVNGIDT DIWNPATDPV VHTHYGPTTL KNRDENRRSI AEFFHLDNDD APIFCVISRL
TWQKGMDLVA NVADEIVAMG GKLVVLGSGE AALEGALLAS ASRHPGRIGV SIGYNEPMSH
LMQAGCDAII IPSRFEPCGL TQLYGLRYGC VPIVARTGGL NDTVIDANHA ALAAKVATGI
QFSPVTETGL LQAIRRAMHF YADRKLWTQL QKQGMKSDVS WEKSAERYAA LYSSLVSKGM