GLGA_RHITR
ID GLGA_RHITR Reviewed; 480 AA.
AC Q9EUT5;
DT 16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
OS Rhizobium tropici.
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=398;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=CIAT899;
RX PubMed=11208782; DOI=10.1128/jb.183.3.854-864.2001;
RA Marroqui S., Zorreguieta A., Santamaria C., Temprano F., Soberon M.,
RA Megias M., Downie J.A.;
RT "Enhanced symbiotic performance by Rhizobium tropici glycogen synthase
RT mutants.";
RL J. Bacteriol. 183:854-864(2001).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; AJ291603; CAC17472.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9EUT5; -.
DR SMR; Q9EUT5; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR UniPathway; UPA00164; -.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..480
FT /note="Glycogen synthase"
FT /id="PRO_0000188639"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 480 AA; 51646 MW; 93405DB405663B26 CRC64;
MKVLSVSSEV FPLIKTGGLA DVVGALPIAL KPYGVETKTL IPGYPAVMKA IRDPVVRLEL
PDLLGEAATI LEVEHAGISF LVLDAPAYYS RTGGPYVDAT GKDYPDNWRR FAALSLAGAE
IAAGLLPGWR PDLVHAHDWQ SALVPVYMRY YPTPELPSVL TIHNIAFQGQ FGADIFPGLR
LPAHAFSVEG IEYYGDVGFL KGGLQTAHAL TTVSPSYAEE ILTPEFGMGL EGVIASKAYN
LYGIVNGIDA DIWNPATDPM IAQTYSAATL KERAINRHRV VEHFGLEEDD GPIFCVVSRL
TWQKGMDILA EVASEVVHMG GKLAILGAGD AALEGALFAA AGRHRGRVGV VGRHNEPMSH
LMQAGCDAII IPSRFEPCGL TQLYGLRSGC LPIVARTGGL NDTIIDANHA ALQAKVATGI
QFSPVTAEGL LQAMRRAMHL FQDRKVWTQM QKQGMKSDVS WGRSAERYAA LYSSLVSRGA