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GLGA_RHITR
ID   GLGA_RHITR              Reviewed;         480 AA.
AC   Q9EUT5;
DT   16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
OS   Rhizobium tropici.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=398;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CIAT899;
RX   PubMed=11208782; DOI=10.1128/jb.183.3.854-864.2001;
RA   Marroqui S., Zorreguieta A., Santamaria C., Temprano F., Soberon M.,
RA   Megias M., Downie J.A.;
RT   "Enhanced symbiotic performance by Rhizobium tropici glycogen synthase
RT   mutants.";
RL   J. Bacteriol. 183:854-864(2001).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AJ291603; CAC17472.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9EUT5; -.
DR   SMR; Q9EUT5; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   UniPathway; UPA00164; -.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT   CHAIN           1..480
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188639"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   480 AA;  51646 MW;  93405DB405663B26 CRC64;
     MKVLSVSSEV FPLIKTGGLA DVVGALPIAL KPYGVETKTL IPGYPAVMKA IRDPVVRLEL
     PDLLGEAATI LEVEHAGISF LVLDAPAYYS RTGGPYVDAT GKDYPDNWRR FAALSLAGAE
     IAAGLLPGWR PDLVHAHDWQ SALVPVYMRY YPTPELPSVL TIHNIAFQGQ FGADIFPGLR
     LPAHAFSVEG IEYYGDVGFL KGGLQTAHAL TTVSPSYAEE ILTPEFGMGL EGVIASKAYN
     LYGIVNGIDA DIWNPATDPM IAQTYSAATL KERAINRHRV VEHFGLEEDD GPIFCVVSRL
     TWQKGMDILA EVASEVVHMG GKLAILGAGD AALEGALFAA AGRHRGRVGV VGRHNEPMSH
     LMQAGCDAII IPSRFEPCGL TQLYGLRSGC LPIVARTGGL NDTIIDANHA ALQAKVATGI
     QFSPVTAEGL LQAMRRAMHL FQDRKVWTQM QKQGMKSDVS WGRSAERYAA LYSSLVSRGA
 
 
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