GLGA_RHOCS
ID GLGA_RHOCS Reviewed; 505 AA.
AC B6IUD9;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=RC1_2746;
OS Rhodospirillum centenum (strain ATCC 51521 / SW).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC Rhodospirillaceae; Rhodospirillum.
OX NCBI_TaxID=414684;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51521 / SW;
RA Touchman J.W., Bauer C., Blankenship R.E.;
RT "Genome sequence of Rhodospirillum centenum.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000613; ACJ00119.1; -; Genomic_DNA.
DR RefSeq; WP_012567899.1; NC_011420.2.
DR AlphaFoldDB; B6IUD9; -.
DR SMR; B6IUD9; -.
DR STRING; 414684.RC1_2746; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ACJ00119; ACJ00119; RC1_2746.
DR KEGG; rce:RC1_2746; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_5; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001591; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..505
FT /note="Glycogen synthase"
FT /id="PRO_1000126094"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 505 AA; 53444 MW; 7917C3782406C5D0 CRC64;
MRVLFVASEC FPYVKTGGLA DVVAALPAAL RELGIDARLL LPGYPPVLAA LGEARPLRDL
PPLPGAGVPG GRLLAGTGTA DGARGPGALD PAVPLYALDL PAFFGRGGNP YSDADGTDWP
DNALRFASLS AAAARIGLEG DGEGWRPEII HAHDWQTGLV PAYLRFAAER TGAKRPVSVF
TIHNLAFQGL VPPALLADLD LPPHSFSIHG LEFHGKIGLL KAGLYYADKL TTVSPTYAQE
IQGPAMGFGL DGLLRARARD LSGILNGVDL GLWNPASDPL IPARYDATLL EARQAAKAEL
RHAFGLGSVP DGPLFAVVSR LTHQKGIDLV LEALPRLLAL GGQLAILGTG DKVLEQAAAA
AMHDHPGRVG LVRAYDEALS HRIQAGADVL LVPSRFEPCG LTQMYALRYG ALPLVSRVGG
LADTVTDVTE SSLADGSATG FVFEPVGLMP LIHAMERAAA LWRRPDLWRT VQRNAMGRDV
GWAASARHYA DLYRQAVMDT TLLSK