GLGA_RHOP2
ID GLGA_RHOP2 Reviewed; 482 AA.
AC Q2J308;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=RPB_0441;
OS Rhodopseudomonas palustris (strain HaA2).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Rhodopseudomonas.
OX NCBI_TaxID=316058;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HaA2;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Pelletier D.A.,
RA Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.;
RT "Complete sequence of Rhodopseudomonas palustris HaA2.";
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000250; ABD05152.1; -; Genomic_DNA.
DR RefSeq; WP_011439342.1; NC_007778.1.
DR AlphaFoldDB; Q2J308; -.
DR SMR; Q2J308; -.
DR STRING; 316058.RPB_0441; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABD05152; ABD05152; RPB_0441.
DR KEGG; rpb:RPB_0441; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_4_5; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000008809; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..482
FT /note="Glycogen synthase"
FT /id="PRO_0000241799"
FT BINDING 18
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 482 AA; 51206 MW; C135D89A954EEAB6 CRC64;
MSALTALSIA SEIFPLIKTG GLADVTGALP TALKPHGIAM RTLVPGYPAV LGGIENPQQV
HSFADFFGGS ARLLAARCDE LELLVLDAPH LYVRPGNPYV GPDGKDWPDN ALRFAALAQA
GAAIGQGLLL GYAPDILHAH DWQTGLVPAY LAYSGRPAPK CVFTIHNLAY QGQFPYELLT
RIGLPERAFS LDGVEYYGGI GYLKAGLQLA DRITTVSPTY ALEIQGPDAG MGLEGLLRLR
ADRLSGILNG IDTRVWDPTA DELIPATYDI ETIGARARNK QALQSRFGLR NAPDALLYGV
ISRLSWQKGL DMLLDVLPGM LAEGAQLALL GAGDTPLEQG FRAAALKYPG QVGAVIGYDE
ALAHQIQAGA DALLVPSRFE PCGLTQLCAL RYGAVPVVAR VGGLADTVVD ANEMAIATGV
ATGVQFSPVT AQMLAKALTK TAALHADHAA WRNLQINGMT TDVSWKNPAQ HYARLYRELI
DA
