GLGA_RHOPT
ID GLGA_RHOPT Reviewed; 483 AA.
AC B3Q9C2;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Rpal_0386;
OS Rhodopseudomonas palustris (strain TIE-1).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Rhodopseudomonas.
OX NCBI_TaxID=395960;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TIE-1;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Emerson D.,
RA Newman D.K., Roden E., Richardson P.;
RT "Complete sequence of Rhodopseudomonas palustris TIE-1.";
RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001096; ACE98946.1; -; Genomic_DNA.
DR RefSeq; WP_012494111.1; NC_011004.1.
DR AlphaFoldDB; B3Q9C2; -.
DR SMR; B3Q9C2; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ACE98946; ACE98946; Rpal_0386.
DR KEGG; rpt:Rpal_0386; -.
DR HOGENOM; CLU_009583_18_4_5; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR BioCyc; RPAL395960:RPAL_RS01945-MON; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001725; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..483
FT /note="Glycogen synthase"
FT /id="PRO_1000126095"
FT BINDING 18
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 483 AA; 51044 MW; FD5B3EE17236EF52 CRC64;
MTTLAVLSVA SELFPLIKTG GLADVAGALP AALRANDVAV TSLLPGYPAV LGGIEDPQQV
HSFNELFGGT ARLLAARCGD LDLFVLDAPH LYVRPGNPYV GPDGKDWPDN GLRFAALAQV
GAALGQGLLP HYKPDVLHAH DWQTGLLPAY LKYSGRPGPK TVFTIHNLAF QGRFPYELLG
RLGLPERAFG LDGIEYYGGI GYLKAGLQLA DRITTVSPSY AAEIQGSEAG MGLDGLLQLR
ADRLSGILNG IDTDVWNPAS DALISATYDV ESIAARARNK KVLQARFGLK PEPGALLYGV
ISRLSWQKGL DLLLQALPQL IGGGAQLALL GSGDAELEQG YAAAARKYPG QVGAVIGYDE
ALAHQIQAGA DALLVPSRFE PCGLTQLCAL RYGAVPVVAR VGGLADTVVD ANEMATATGV
ATGVQFAPVT TDALIKAFGK TRALFADVVA WRNLQINGMT TDVSWKNPAQ HYAKLYRDLV
AER
