GLGA_SYNC1
ID GLGA_SYNC1 Reviewed; 484 AA.
AC Q3A0B8;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=Pcar_2954;
OS Syntrophotalea carbinolica (strain DSM 2380 / NBRC 103641 / GraBd1)
OS (Pelobacter carbinolicus).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC Syntrophotaleaceae; Syntrophotalea.
OX NCBI_TaxID=338963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2380 / NBRC 103641 / GraBd1;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F.,
RA Land M., Kyrpides N., Ivanova N., Richardson P.;
RT "Complete sequence of Pelobacter carbinolicus DSM 2380.";
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000142; ABA90189.1; -; Genomic_DNA.
DR RefSeq; WP_011342742.1; NC_007498.2.
DR AlphaFoldDB; Q3A0B8; -.
DR SMR; Q3A0B8; -.
DR STRING; 338963.Pcar_2954; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABA90189; ABA90189; Pcar_2954.
DR KEGG; pca:Pcar_2954; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_7; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000002534; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..484
FT /note="Glycogen synthase"
FT /id="PRO_0000230251"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 484 AA; 53725 MW; 80D0664ED723F778 CRC64;
MNILLAASEV APFAKTGGLA DVAGALPQEL HRLGHDVRII MPLYRSVRKQ HLSLQHLGEL
PAVKMGDAIR TGRLWQGSLQ DVPVYFLEQD DYFDRDGLYG TSQNDYPDNA ERFGFFGRGL
LAALPQIGFK PEILHLNDWQ TGLVPALLRT EWAEDPFYAG TATMTTIHNL GYQGLFPAET
VATLGLDPAL YTMEGLEYYD QVSFLKSGLV YADMITTVSE TYCAEIQTPQ MGHGFDGILH
ARAARLFGVL NGIDDKLWNP QCDPALTAPY SVDDLEGKAA NKRQLQKQLG LSCDADVPLL
TMVTRLASQK GLDLVEQAWE QLLQRGVQLV ILGSGDQDFM DRFAQLGAQH PTQTAVRLGF
DDRLARLIYA GSDMFLMPSH YEPCGLGQLI ALRYGSVPVV RKTGGLADTV FDPQDQATQA
NGFTFREISP SAMLAALDRA LALYRQPEGW KQLVRRGMQG DFSWRQSALR YVELYRKAVE
LHHA
