ID   GLGA_SYNP6              Reviewed;         465 AA.
AC   Q5N1P1;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=syc1589_d;
OS   Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS   nidulans).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=269084;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX   PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA   Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA   Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT   "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT   Synechococcus elongatus PCC 6301 chromosome: gene content and
RT   organization.";
RL   Photosyn. Res. 93:55-67(2007).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AP008231; BAD79779.1; -; Genomic_DNA.
DR   RefSeq; WP_011243899.1; NC_006576.1.
DR   AlphaFoldDB; Q5N1P1; -.
DR   SMR; Q5N1P1; -.
DR   STRING; 269084.syc1589_d; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; BAD79779; BAD79779; syc1589_d.
DR   KEGG; syc:syc1589_d; -.
DR   eggNOG; COG0297; Bacteria.
DR   OMA; TWCPWYM; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000001175; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT   CHAIN           1..465
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188652"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   465 AA;  53287 MW;  99C9DD6616652D7B CRC64;
     MRILFVAAEC APFAKVGGMG DVVGSLPKVL KALGHDVRIF MPYYGFLNSK LDIPAEPIWW
     GYAMFNHFAV YETQLPGSDV PLYLMGHPAF DPHRIYSGED EDWRFTFFAN GAAEFSWNYW
     KPQVIHCHDW HTGMIPVWMH QSPDISTVFT IHNLAYQGPW RWKLEKITWC PWYMQGDSTM
     AAALLYADRV NTVSPTYAQQ IQTPTYGEKL EGLLSFISGK LSGILNGIDV DSYNPATDTR
     IVANCDRDTL DKRLNNKLAL QKEMGLEVNP DRFLIGFVAR LVEQKGIDLL LQILDRFLSY
     SDAQFVVLGT GERYYETQLW ELATRYPGRM STYLMYDEGL SRRIYAGSDA FLVPSRFEPC
     GITQMLALRY GSVPIVRRTG GLVDTVFHHD PRHAEGNGYC FDRYEPLDLY TCLVRAWESY
     QYQPQWQKLQ QRGMAVDLSW KQSAIAYEQL YAEAIGLPID VLQEA