GLGA_SYNPW
ID GLGA_SYNPW Reviewed; 524 AA.
AC A5GKI7;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN OrderedLocusNames=SynWH7803_1026;
OS Synechococcus sp. (strain WH7803).
OC Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC unclassified Synechococcus.
OX NCBI_TaxID=32051;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH7803;
RG Genoscope;
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CT971583; CAK23452.1; -; Genomic_DNA.
DR RefSeq; WP_011932934.1; NC_009481.1.
DR AlphaFoldDB; A5GKI7; -.
DR SMR; A5GKI7; -.
DR STRING; 32051.SynWH7803_1026; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAK23452; CAK23452; SynWH7803_1026.
DR KEGG; syx:SynWH7803_1026; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_3; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001566; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..524
FT /note="Glycogen synthase"
FT /id="PRO_1000014386"
FT REGION 463..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 524 AA; 58577 MW; C7505D9DF20093B4 CRC64;
MRVLFAAAEC APMVKVGGMG DVVGSLPPAL AQLGHDVRLI MPGYGKLWSS LDIPAEPIWR
AQTMGTEFAV FETRHPTNGL PLYLVGHPVF DPERIYGGED EDWRFTFFAS AAAEFSWNVW
KPQVLHCHDW HTGMIPVWMH QDPEISTVFT IHNLKYQGPW RWKLDRITWC PWYMQGDHTM
AAALLYADRV NAVSPTYAQE IRTSEYGEKL EGLLNYISGK LRGILNGIDL EAWNPATDKA
LPATFSSANL AGKATCKQVL QERMGLTLNP DTFLLGMVSR LVDQKGVDLL LQVADRLLAY
TDTQIVVLGT GDRGLESGLW QLASRHPGRV AVFLTYDDAL SRLIYAGSDA FLMPSRFEPC
GISQLYAMRY GCVPVVRKVG GLVDTVPPHD PRQKSGTGFC FDRFEPVDFY TALVRAWEAF
RHPESWKELQ RRGMEQDYSW ARSALEYDRM YRDVCGLKEP SPDAAAVEQF SQGQEADPSR
HGGASQTLSP SEEAPIESSE ASSGSTPVRT SRNPLARLLG KQRR
