GLGA_SYNR3
ID GLGA_SYNR3 Reviewed; 507 AA.
AC A5GT38;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN OrderedLocusNames=SynRCC307_1144;
OS Synechococcus sp. (strain RCC307).
OC Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC unclassified Synechococcus.
OX NCBI_TaxID=316278;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC307;
RG Genoscope;
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CT978603; CAK28047.1; -; Genomic_DNA.
DR RefSeq; WP_011935561.1; NC_009482.1.
DR AlphaFoldDB; A5GT38; -.
DR SMR; A5GT38; -.
DR STRING; 316278.SynRCC307_1144; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAK28047; CAK28047; SynRCC307_1144.
DR KEGG; syr:SynRCC307_1144; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_3; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001115; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..507
FT /note="Glycogen synthase"
FT /id="PRO_1000014387"
FT REGION 475..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 507 AA; 57101 MW; 9E814EB3C7E04AD4 CRC64;
MRILFAAAEC APMVKVGGMG DVVGSLPPAL AELGHDVRVI MPGYGKLWSQ LDVPSEPIWR
AQTMGTDFAV YETRHPKTGL TIYLVGHPVF DGERIYGGED EDWRFTFFAS ATSEFAWNAW
KPQVLHCHDW HTGMIPVWMH QDPEISTVFT IHNLKYQGPW RWKLERMTWC PWYMQGDHTM
AAALLYADRV NAVSPTYAQE IRTPEYGEQL EGLLNYISGK LRGILNGIDV EAWNPATDSR
IPATYSTADL SGKAVCKRAL QERMGLQVNP DTFVIGLVSR LVDQKGVDLL LQVAERFLAY
TDTQIVVLGT GDRHLESGLW QMASQHSGRF ASFLTYDDDL SRLIYAGSDA FLMPSRFEPC
GISQLLSMRY GTIPVVRRVG GLVDTVPPYV PATQEGNGFC FDRYEAIDLY TALVRAWEAY
RHQDSWQQLM KRVMQVDFSW ARSALEYDRM YRDVCGMKEP TPEADAVAAF SIPQPPEQQA
ARAAAEAADP NPQRRFNPLG LLRRNGG
