ID   GLGA_SYNS3              Reviewed;         518 AA.
AC   Q0I9Y8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=sync_1529;
OS   Synechococcus sp. (strain CC9311).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=64471;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC9311;
RX   PubMed=16938853; DOI=10.1073/pnas.0602963103;
RA   Palenik B., Ren Q., Dupont C.L., Myers G.S., Heidelberg J.F., Badger J.H.,
RA   Madupu R., Nelson W.C., Brinkac L.M., Dodson R.J., Durkin A.S.,
RA   Daugherty S.C., Sullivan S.A., Khouri H., Mohamoud Y., Halpin R.,
RA   Paulsen I.T.;
RT   "Genome sequence of Synechococcus CC9311: insights into adaptation to a
RT   coastal environment.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:13555-13559(2006).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; CP000435; ABI46119.1; -; Genomic_DNA.
DR   RefSeq; WP_011619451.1; NC_008319.1.
DR   AlphaFoldDB; Q0I9Y8; -.
DR   SMR; Q0I9Y8; -.
DR   STRING; 64471.sync_1529; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   PRIDE; Q0I9Y8; -.
DR   EnsemblBacteria; ABI46119; ABI46119; sync_1529.
DR   KEGG; syg:sync_1529; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_2_3; -.
DR   OMA; TWCPWYM; -.
DR   OrthoDB; 83240at2; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000001961; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..518
FT                   /note="Glycogen synthase"
FT                   /id="PRO_1000014388"
FT   REGION          469..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        472..502
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   518 AA;  58096 MW;  E0D05021049197E7 CRC64;
     MRVLFAAAEC APMVKVGGMG DVVGSLPPAL KALGHDVRLI MPGYGKLWSR LEIPAEPIWR
     GQTMGTEFAV FETRHPTNGL TIYLVGHPVF DPERIYGGED EDWRFTFFAS AAAEFAWNVW
     KPNVLHCHDW HTGMIPVWMH QDPEISTVYT IHNLKYQGPW RWKLDRMTWC PWYMQGDHTM
     AAALLYADGV NAVSPTYSRE IRTSEYSEKL DGLLNYISGK LRGILNGIDL EAWNPATDRA
     LPATFSADDL SGRARNKQVL QERMGLEVRP DAYLLGMVSR LVDQKGVDLL LQVADRLLAY
     TDTQIVVLGT GDRGLESGLW QMASRHPGRV SVFLTYDDDL SRLIYAGSDA FLMPSRFEPC
     GISQLLAMRY GCVPVVRKVG GLVDTVPPHD PAQQSGTGFC FDRFDPVDFF TALVRSWEAF
     RHQDSWRELQ RRGMRQDYSW ARSAMEYDQM YREVCGLKEP GPDAAAVEQF SQGQDADPSL
     AQGQHAAPTS PPEQSSEDLS KGPGSRNPLA KLFGGQRR