GLGA_SYNSC
ID GLGA_SYNSC Reviewed; 511 AA.
AC Q3AKK1;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN OrderedLocusNames=Syncc9605_1126;
OS Synechococcus sp. (strain CC9605).
OC Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC unclassified Synechococcus.
OX NCBI_TaxID=110662;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC9605;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F.,
RA Land M., Kyrpides N., Ivanova N., Richardson P.;
RT "Complete sequence of Synechococcus sp. CC9605.";
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP000110; ABB34881.1; -; Genomic_DNA.
DR RefSeq; WP_011364102.1; NC_007516.1.
DR AlphaFoldDB; Q3AKK1; -.
DR SMR; Q3AKK1; -.
DR STRING; 110662.Syncc9605_1126; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; ABB34881; ABB34881; Syncc9605_1126.
DR KEGG; syd:Syncc9605_1126; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_3; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT CHAIN 1..511
FT /note="Glycogen synthase"
FT /id="PRO_0000241800"
FT REGION 470..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 511 AA; 57335 MW; 18AA0AE8377D0D42 CRC64;
MRILFAAAEC APMIKVGGMG DVVGSLPPAL AKLGHDVRLI MPGYAKLWSR LNVPADPIWR
AQTMGTEFAV YETKHPTNGM TIYLVGHPVF DPERIYGGED EDWRFTFFAS AAAEFSWNVW
KPQVLHCHDW HTGMIPVWMH QDPDISTVFT IHNLKYQGPW RWKLDRMTWC PWYMQGDHTM
AAALLYADRV NGVSPTYAQE IRTAEYGEKL EGLLNVVSGK LRGILNGIDL DAWDPATDRS
LPANFSADDL YGKAVCKKVL QERMGLEVRE DAFVLGMVSR LVDQKGVDLL LQVADRLLAY
TDTQIVVLGT GDRGLESGLW QLASRHPGKC AVFLTYDDDL SRLIYGGSDA FLMPSRFEPC
GISQLYAMRY GSVPVVRKVG GLVDTVPPHI PAADSGTGFC FDRFEPVDFY TALVRAWEAF
RHRDSWTELQ KRGMNQDYSW DRSAVDYDLM YKDVCGIKEP TPDAALVEQF SQGQAADPSR
SEAQTEETRV PAEVTSAGRN PLNRLFGRRS S
