ID   GLGA_THEVB              Reviewed;         474 AA.
AC   Q8DKU2;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=tll0763;
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; BA000039; BAC08314.1; -; Genomic_DNA.
DR   RefSeq; NP_681552.1; NC_004113.1.
DR   RefSeq; WP_011056608.1; NC_004113.1.
DR   AlphaFoldDB; Q8DKU2; -.
DR   SMR; Q8DKU2; -.
DR   STRING; 197221.22294484; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; BAC08314; BAC08314; BAC08314.
DR   KEGG; tel:tll0763; -.
DR   PATRIC; fig|197221.4.peg.802; -.
DR   eggNOG; COG0297; Bacteria.
DR   OMA; TWCPWYM; -.
DR   OrthoDB; 83240at2; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..474
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188651"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   474 AA;  54364 MW;  46FCDB64E5B7609B CRC64;
     MRILFVAAEA APLAKVGGMG DVVGSLPKVL RRMGHDVRIF MPYYGFLPDK VEIPKDPIWI
     GHAMFQTFHV YETVLPGSDV PLYLFGHPCF NPRRIYYGED EDWRFTFFAN GAAEFAWNYW
     KPQIIHCHDW HTGMIPVWMH QDPDITTVFT IHNLAYQGPW RWRLEQITWC PWYMQGHNTM
     AAALQYADRV NTVSPTYAEQ IKTPEYGEKL EGLLSFISGK LSGILNGIDT ELFDPSSDRA
     LAQNYTADTL ERRRANKIAL QEELGLEVNS GAFLVGMVSR LVEQKGLDLL IQILDRFLAY
     TDSQFVLLGT GDRYYETQMW QIASRFPGRC SVQLLYSDVL SRRIYGGADA FIMPSRFEPC
     GISQMIALRY GCVPIVRRTG GLVDTVSHHN PEQQTGTGYC FDRYEPLDFY TCLVRAWEGY
     RYKREWHALQ QRGMREDFSW TKSALAYNAL YNSIYGLPPE TMPNPSPTLV PAVT