GLGA_THEYD
ID GLGA_THEYD Reviewed; 497 AA.
AC B5YG91;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=THEYE_A1492;
OS Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87).
OC Bacteria; Nitrospirae; Thermodesulfovibrionia; Thermodesulfovibrionales;
OC Thermodesulfovibrionaceae; Thermodesulfovibrio.
OX NCBI_TaxID=289376;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51303 / DSM 11347 / YP87;
RA Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.;
RT "The complete genome sequence of Thermodesulfovibrio yellowstonii strain
RT ATCC 51303 / DSM 11347 / YP87.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; CP001147; ACI21910.1; -; Genomic_DNA.
DR RefSeq; WP_012546609.1; NC_011296.1.
DR RefSeq; YP_002249289.1; NC_011296.1.
DR AlphaFoldDB; B5YG91; -.
DR SMR; B5YG91; -.
DR STRING; 289376.THEYE_A1492; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR PRIDE; B5YG91; -.
DR EnsemblBacteria; ACI21910; ACI21910; THEYE_A1492.
DR KEGG; tye:THEYE_A1492; -.
DR PATRIC; fig|289376.4.peg.1451; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_0; -.
DR InParanoid; B5YG91; -.
DR OMA; TWCPWYM; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000000718; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..497
FT /note="Glycogen synthase"
FT /id="PRO_1000126110"
FT BINDING 15
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 497 AA; 56159 MW; 80CEC22A2FB9A8F5 CRC64;
MKLALVSAEA YPFSKTGGLG DVVGSLFKEF IKAGIDVTLF LPFYKITRDN FSNSVVNAEI
VYGAPIGLNT LFGAVRVAKV SVDSDDNLII EPSKKGNLFF IEHNNFFDRN ELYGTNHGEY
LDNAERFVFF SRAVLEICKI MNLNFDVIHC HDWHTALIPL YLKTLYRECS CFEKTKTVLT
VHNLGYQGIF PREKLELTGF GQEMFHIDGL EFYGMVNFLK GGLFNADIIT TVSPTYAKEI
LTPDYGAGLD GVLRKRKENL VGIINGIDYK IWNPEEDPFI AKKYGLQNIN DKQKNKEDLI
ALAGINSSLQ DPIIAFIGRM VYQKGIDIVV DAMPNLIKNG ISFIFEGTGE SYYEHKIREL
QNSYPSKVFA FIGFDEALAH KIYAGADSLL VPSRYEPCGL SQLIAMRYGT IPICRKTGGL
SDTVEDKVTG FLFSEYSSSA LTHAISRFIE IYNNKQKFLE MIREAMKRDF SWSNSSKKYI
ELYRGLIGER ERKTGTI
