GLGA_VIBA3
ID GLGA_VIBA3 Reviewed; 484 AA.
AC B7VM42;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=VS_1083;
OS Vibrio atlanticus (strain LGP32) (Vibrio splendidus (strain Mel32)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=575788;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LGP32;
RA Mazel D., Le Roux F.;
RT "Vibrio splendidus str. LGP32 complete genome.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
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DR EMBL; FM954972; CAV18193.1; -; Genomic_DNA.
DR RefSeq; WP_012603611.1; NC_011753.2.
DR AlphaFoldDB; B7VM42; -.
DR SMR; B7VM42; -.
DR STRING; 575788.VS_1083; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; CAV18193; CAV18193; VS_1083.
DR KEGG; vsp:VS_1083; -.
DR PATRIC; fig|575788.5.peg.2407; -.
DR eggNOG; COG0297; Bacteria.
DR HOGENOM; CLU_009583_18_2_6; -.
DR OMA; MPSRWEP; -.
DR OrthoDB; 83240at2; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000009100; Chromosome 1.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..484
FT /note="Glycogen synthase"
FT /id="PRO_1000190092"
FT BINDING 20
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 484 AA; 54097 MW; 0ABB2EACE7E1B041 CRC64;
MVTKTLSVLF VASEVEGLIK SGGLADVAKA LPKALQTLEQ DVRVTIPAYR NIPNIDSAEV
ILSTELDHWP HTAYQVKKLS VEGVQIFAIE CAKYFDRPEM YAENNQAYAD NGERFSFFST
ACLDMLPKLA FQPDIIHAND WHTGFVPFLL KSRYQQHDFF ENTRSVISIH NAVFKGVFAY
DELQCLSEMH SYNVPEASVS DTHVTMLKAG VMCADKINAV SPTYAEELKT ELGSHGMAAE
FQHRSADLFG ILNGCDYGAW NPETDAFLPR KFKATKHSMT RGKSACKQKL QQDVGLPVTD
CAVYGMVCRL TNQKGVHYLL PIIEQFLKNE LQIVIVGTGD PVLASQLKEL SALHSDKFSF
VEAYNNELAH LVEAGSDFFL MPSEFEPCGL NQIYSMAYGT LPIVRSVGGL KDSVNDYDQE
PEIATGFAFE EPTPQALLAV LHRSLLLYAQ NPSEIKRVQL YAMQQDFSWE DAAEEYLAMY
HSAF
