ID   GLGA_VIBVU              Reviewed;         485 AA.
AC   Q8DAR0;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 2.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=VV1_2132;
OS   Vibrio vulnificus (strain CMCP6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=216895;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CMCP6;
RA   Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.;
RT   "Complete genome sequence of Vibrio vulnificus CMCP6.";
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AE016795; AAO10518.2; -; Genomic_DNA.
DR   AlphaFoldDB; Q8DAR0; -.
DR   SMR; Q8DAR0; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; AAO10518; AAO10518; VV1_2132.
DR   KEGG; vvu:VV1_2132; -.
DR   HOGENOM; CLU_009583_18_2_6; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000002275; Chromosome 1.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT   CHAIN           1..485
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188662"
FT   BINDING         20
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   485 AA;  54244 MW;  15BEDEEBFECDAE9F CRC64;
     MATNPLSILF VASEVEGLIK SGGLADVAKA LPEALVNLQH DARIAIPAYT AIPDVCDDEV
     ILDTHLETWP HTHYQVKKRF LGDNPVYLIA CGHYFDRPSM YAENNQAYTD NGERFAFFSA
     ACLDMLPKIG FQPDIVHAND WHTGLVPFLL KHRYGQDPFF AQTKSILSIH NAVFKGVFHY
     DEMQCLPEFH CRNVPDAAVS STHMTMLKAG VMNADKINAV SPTYAEELKT ELGSHGMAWE
     FQQRAGDLVG ILNGCDYSAW HPDTDSYLPI NYKATKQSMV RGKNGCKRAL QEQVGLPIKD
     VAMFGMVCRL THQKGVHYLL PVLTEFLKLD VQLVLVGTGD PLLAAQLRDV AAQFGEKFVF
     VEAYNNQLAH LVEAASDFFL MPSEFEPCGL NQIYSMAYGS LPIVRGVGGL KDSVCDYDVN
     PETATGFVFY EPTAQALLIT MQRALLLYAQ NLTELRRVQL YAMERDFCWN KAAEQYVELY
     RSALK