GLGA_XANOR
ID GLGA_XANOR Reviewed; 509 AA.
AC Q5H6Q4;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 2.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=XOO0112;
OS Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=291331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KACC10331 / KXO85;
RX PubMed=15673718; DOI=10.1093/nar/gki206;
RA Lee B.-M., Park Y.-J., Park D.-S., Kang H.-W., Kim J.-G., Song E.-S.,
RA Park I.-C., Yoon U.-H., Hahn J.-H., Koo B.-S., Lee G.-B., Kim H.,
RA Park H.-S., Yoon K.-O., Kim J.-H., Jung C.-H., Koh N.-H., Seo J.-S.,
RA Go S.-J.;
RT "The genome sequence of Xanthomonas oryzae pathovar oryzae KACC10331, the
RT bacterial blight pathogen of rice.";
RL Nucleic Acids Res. 33:577-586(2005).
CC -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00484}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_00484}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAW73366.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE013598; AAW73366.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; Q5H6Q4; -.
DR SMR; Q5H6Q4; -.
DR STRING; 291331.XOO0112; -.
DR CAZy; GT5; Glycosyltransferase Family 5.
DR EnsemblBacteria; AAW73366; AAW73366; XOO0112.
DR KEGG; xoo:XOO0112; -.
DR HOGENOM; CLU_009583_18_4_6; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000006735; Chromosome.
DR GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00484; Glycogen_synth; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR011835; GS/SS.
DR InterPro; IPR013534; Starch_synth_cat_dom.
DR Pfam; PF08323; Glyco_transf_5; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR TIGRFAMs; TIGR02095; glgA; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW Transferase.
FT CHAIN 1..509
FT /note="Glycogen synthase"
FT /id="PRO_0000230274"
FT BINDING 47
FT /ligand="ADP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:57498"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ SEQUENCE 509 AA; 54806 MW; 0B1DFE3538924A7C CRC64;
MLPALKKGGR PRDALGRFIR HHERLPVSLA DTRGVLFVVS EMADFIKAGG LGDVAAALPR
ALRHRYDVRV LIPGYRAVLE RAGKVEIVGR VLAHAALPAC DIGRIVQSDG LPIYILLSRE
LFERDGSPYV STSGSEFEDN AIRFATLSHA AADIAAGHAG LGWKPRLLHL NDWPCALAAG
YVRWSGGTTP CLLTIHNLAY QGLVPYSMAG ALGIPAERVA ELEFYGQMSF LRGGIVNADH
VNTVSVSYAK QITGPAQGCG LDRLLAGRAA KGALTGIVNG IDASWDPRTD EYLDSHFSVN
QWQGRQDNAA QVRKAFGLRE STGPLFAVVS RLVHQKGLDL ICEVAPQIVA AGGQIAVIGG
GEPDIERQVA ELTRRYPGQV GAFIGFEEGL ARRMFAGADF LLMPSRFEPC GLSQMYAQRF
GCLPIAHATG GLIDTVDDGV TGFLFQHASV EALRRCLERA FRTFRLPGLL AAMRRAAMLR
PSGWDVAGNK YLSLYERTAA IAPALATVS