ID   GLGC_BACCL              Reviewed;         250 AA.
AC   P30522;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Glucose-1-phosphate adenylyltransferase;
DE            EC=2.7.7.27;
DE   AltName: Full=ADP-glucose pyrophosphorylase;
DE            Short=ADPGlc PPase;
DE   AltName: Full=ADP-glucose synthase;
DE   Flags: Fragment;
GN   Name=glgC;
OS   Bacillus caldolyticus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   Geobacillus thermoleovorans group.
OX   NCBI_TaxID=1394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1296817; DOI=10.3109/10425179209034021;
RA   Kiel J.A.K.W., Boels J.M., Beldman G., Venema G.;
RT   "The glgB gene from the thermophile Bacillus caldolyticus encodes a
RT   thermolabile branching enzyme.";
RL   DNA Seq. 3:221-232(1992).
CC   -!- FUNCTION: Catalyzes the synthesis of ADP-glucose, a sugar donor used in
CC       elongation reactions on alpha-glucans. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose
CC         + diphosphate; Xref=Rhea:RHEA:12120, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57498,
CC         ChEBI:CHEBI:58601; EC=2.7.7.27;
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC   -!- SIMILARITY: Belongs to the bacterial/plant glucose-1-phosphate
CC       adenylyltransferase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z14057; CAA78441.1; -; Genomic_DNA.
DR   PIR; C56639; C56639.
DR   AlphaFoldDB; P30522; -.
DR   SMR; P30522; -.
DR   UniPathway; UPA00164; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR011831; ADP-Glc_PPase.
DR   InterPro; IPR005836; ADP_Glu_pyroP_CS.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR43523; PTHR43523; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
DR   PROSITE; PS00808; ADP_GLC_PYROPHOSPH_1; 1.
DR   PROSITE; PS00809; ADP_GLC_PYROPHOSPH_2; 1.
DR   PROSITE; PS00810; ADP_GLC_PYROPHOSPH_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Carbohydrate metabolism; Glycogen biosynthesis;
KW   Glycogen metabolism; Nucleotide-binding; Nucleotidyltransferase;
KW   Transferase.
FT   CHAIN           1..>250
FT                   /note="Glucose-1-phosphate adenylyltransferase"
FT                   /id="PRO_0000195277"
FT   NON_TER         250
SQ   SEQUENCE   250 AA;  28215 MW;  A5ADBA087EB873F7 CRC64;
     MKKKCIAMLL AGGQGSRLRS LTKNIAKPAV PFGGKYRIID FTLSNCTNSG IDTVGVLTQY
     QPLLLHSYIG IGSAWDLDRR NGGVTVLPPY SASSGVKWYE GTANAIYQNM NYIEQYDPDY
     VLVLSGDHIY KMDYQQMLDY HIAKQADATI SVIEVPWEEA SRFGIMNTNE NMEIVEFAEK
     PANPKSNLAS MGIYIFNWPL LREYLQIDNA DPHSSHDFGK DVIPRLLREN KRLVAYPFKG
     YWKDVGTVKS