ID   GLGS_ECO45              Reviewed;          66 AA.
AC   B7MAC5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Surface composition regulator {ECO:0000255|HAMAP-Rule:MF_00525};
GN   Name=glgS {ECO:0000255|HAMAP-Rule:MF_00525}; OrderedLocusNames=ECS88_3446;
OS   Escherichia coli O45:K1 (strain S88 / ExPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585035;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S88 / ExPEC;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- FUNCTION: Major determinant of cell surface composition. Negatively
CC       regulates motility, adhesion and synthesis of biofilm
CC       exopolysaccharides. {ECO:0000255|HAMAP-Rule:MF_00525}.
CC   -!- SIMILARITY: Belongs to the GlgS family. {ECO:0000255|HAMAP-
CC       Rule:MF_00525}.
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DR   EMBL; CU928161; CAR04675.1; -; Genomic_DNA.
DR   RefSeq; WP_001296424.1; NC_011742.1.
DR   AlphaFoldDB; B7MAC5; -.
DR   SMR; B7MAC5; -.
DR   EnsemblBacteria; CAR04675; CAR04675; ECS88_3446.
DR   KEGG; ecz:ECS88_3446; -.
DR   HOGENOM; CLU_185971_0_0_6; -.
DR   OMA; HRSWFCK; -.
DR   Proteomes; UP000000747; Chromosome.
DR   GO; GO:1902201; P:negative regulation of bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-UniRule.
DR   GO; GO:1900191; P:negative regulation of single-species biofilm formation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.970.20; -; 1.
DR   HAMAP; MF_00525; GlgS; 1.
DR   InterPro; IPR015065; GlgS.
DR   InterPro; IPR036295; GlgS_sf.
DR   Pfam; PF08971; GlgS; 1.
DR   SUPFAM; SSF109747; SSF109747; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..66
FT                   /note="Surface composition regulator"
FT                   /id="PRO_1000127734"
SQ   SEQUENCE   66 AA;  7922 MW;  9147AB6E7AD6753F CRC64;
     MDHSLNSLNN FDFLARSFAR MHAEGRPVDI LAVTGNMDEE HRTWFCARYA WYCQQMMQTR
     ELELEH