ID   GLGS_ECO5E              Reviewed;          66 AA.
AC   B5YR89;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Surface composition regulator {ECO:0000255|HAMAP-Rule:MF_00525};
GN   Name=glgS {ECO:0000255|HAMAP-Rule:MF_00525};
GN   OrderedLocusNames=ECH74115_4358;
OS   Escherichia coli O157:H7 (strain EC4115 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=444450;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EC4115 / EHEC;
RX   PubMed=22135463; DOI=10.1073/pnas.1107176108;
RA   Eppinger M., Mammel M.K., Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Genomic anatomy of Escherichia coli O157:H7 outbreaks.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20142-20147(2011).
CC   -!- FUNCTION: Major determinant of cell surface composition. Negatively
CC       regulates motility, adhesion and synthesis of biofilm
CC       exopolysaccharides. {ECO:0000255|HAMAP-Rule:MF_00525}.
CC   -!- SIMILARITY: Belongs to the GlgS family. {ECO:0000255|HAMAP-
CC       Rule:MF_00525}.
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DR   EMBL; CP001164; ACI39238.1; -; Genomic_DNA.
DR   RefSeq; WP_001296424.1; NC_011353.1.
DR   AlphaFoldDB; B5YR89; -.
DR   SMR; B5YR89; -.
DR   KEGG; ecf:ECH74115_4358; -.
DR   HOGENOM; CLU_185971_0_0_6; -.
DR   OMA; HRSWFCK; -.
DR   GO; GO:1902201; P:negative regulation of bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-UniRule.
DR   GO; GO:1900191; P:negative regulation of single-species biofilm formation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.970.20; -; 1.
DR   HAMAP; MF_00525; GlgS; 1.
DR   InterPro; IPR015065; GlgS.
DR   InterPro; IPR036295; GlgS_sf.
DR   Pfam; PF08971; GlgS; 1.
DR   SUPFAM; SSF109747; SSF109747; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..66
FT                   /note="Surface composition regulator"
FT                   /id="PRO_1000127735"
SQ   SEQUENCE   66 AA;  7922 MW;  9147AB6E7AD6753F CRC64;
     MDHSLNSLNN FDFLARSFAR MHAEGRPVDI LAVTGNMDEE HRTWFCARYA WYCQQMMQTR
     ELELEH