GLGS_ECOBW
ID GLGS_ECOBW Reviewed; 66 AA.
AC C4ZQW6;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 65.
DE RecName: Full=Surface composition regulator {ECO:0000255|HAMAP-Rule:MF_00525};
GN Name=glgS {ECO:0000255|HAMAP-Rule:MF_00525}; OrderedLocusNames=BWG_2760;
OS Escherichia coli (strain K12 / MC4100 / BW2952).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=595496;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MC4100 / BW2952;
RX PubMed=19376874; DOI=10.1128/jb.00118-09;
RA Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R.,
RA Wang L.;
RT "Genomic sequencing reveals regulatory mutations and recombinational events
RT in the widely used MC4100 lineage of Escherichia coli K-12.";
RL J. Bacteriol. 191:4025-4029(2009).
CC -!- FUNCTION: Major determinant of cell surface composition. Negatively
CC regulates motility, adhesion and synthesis of biofilm
CC exopolysaccharides. {ECO:0000255|HAMAP-Rule:MF_00525}.
CC -!- SIMILARITY: Belongs to the GlgS family. {ECO:0000255|HAMAP-
CC Rule:MF_00525}.
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DR EMBL; CP001396; ACR64438.1; -; Genomic_DNA.
DR RefSeq; WP_000350095.1; NC_012759.1.
DR AlphaFoldDB; C4ZQW6; -.
DR SMR; C4ZQW6; -.
DR GeneID; 66673054; -.
DR KEGG; ebw:BWG_2760; -.
DR HOGENOM; CLU_185971_0_0_6; -.
DR OMA; HRSWFCK; -.
DR GO; GO:1902201; P:negative regulation of bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-UniRule.
DR GO; GO:1900191; P:negative regulation of single-species biofilm formation; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.970.20; -; 1.
DR HAMAP; MF_00525; GlgS; 1.
DR InterPro; IPR015065; GlgS.
DR InterPro; IPR036295; GlgS_sf.
DR Pfam; PF08971; GlgS; 1.
DR SUPFAM; SSF109747; SSF109747; 1.
PE 3: Inferred from homology;
FT CHAIN 1..66
FT /note="Surface composition regulator"
FT /id="PRO_1000211760"
SQ SEQUENCE 66 AA; 7892 MW; D047AB6E7AD67523 CRC64;
MDHSLNSLNN FDFLARSFAR MHAEGRPVDI LAVTGNMDEE HRTWFCARYA WYCQQMMQAR
ELELEH