GLIP3_ARATH
ID GLIP3_ARATH Reviewed; 367 AA.
AC Q9SYF5;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 2.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=GDSL esterase/lipase 3;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase 3;
DE Flags: Precursor;
GN Name=GLIP3; OrderedLocusNames=At1g53990; ORFNames=F15I1.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=16126835; DOI=10.1105/tpc.105.034819;
RA Oh I.S., Park A.R., Bae M.S., Kwon S.J., Kim Y.S., Lee J.E., Kang N.Y.,
RA Lee S., Cheong H., Park O.K.;
RT "Secretome analysis reveals an Arabidopsis lipase involved in defense
RT against Alternaria brassicicola.";
RL Plant Cell 17:2832-2847(2005).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD25771.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC006577; AAD25771.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33032.1; -; Genomic_DNA.
DR PIR; D96580; D96580.
DR RefSeq; NP_175801.1; NM_104276.1.
DR AlphaFoldDB; Q9SYF5; -.
DR SMR; Q9SYF5; -.
DR STRING; 3702.AT1G53990.1; -.
DR PaxDb; Q9SYF5; -.
DR PRIDE; Q9SYF5; -.
DR EnsemblPlants; AT1G53990.1; AT1G53990.1; AT1G53990.
DR GeneID; 841837; -.
DR Gramene; AT1G53990.1; AT1G53990.1; AT1G53990.
DR KEGG; ath:AT1G53990; -.
DR Araport; AT1G53990; -.
DR TAIR; locus:2014450; AT1G53990.
DR eggNOG; ENOG502QQ4G; Eukaryota.
DR HOGENOM; CLU_015101_0_2_1; -.
DR InParanoid; Q9SYF5; -.
DR OMA; TGAYECA; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9SYF5; -.
DR BioCyc; ARA:AT1G53990-MON; -.
DR PRO; PR:Q9SYF5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SYF5; baseline and differential.
DR Genevisible; Q9SYF5; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; ISS:TAIR.
DR GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR044552; GLIP1-5/GLL25.
DR InterPro; IPR008265; Lipase_GDSL_AS.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR PANTHER; PTHR45966; PTHR45966; 1.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR PROSITE; PS01098; LIPASE_GDSL_SER; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..367
FT /note="GDSL esterase/lipase 3"
FT /id="PRO_0000367336"
FT ACT_SITE 42
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 329
FT /evidence="ECO:0000250"
FT ACT_SITE 332
FT /evidence="ECO:0000250"
FT CARBOHYD 175
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 194
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 321
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 351
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 367 AA; 41110 MW; 571AFAFEB347293E CRC64;
MVRLVLIIFF VYTIILSIGS INCIDNNNLV TNQAALFVFG DSLFDAGNNN YINTVSSFRS
NIWPYGQTNF KFPTGRLSDG PEKAWLPSIP PNLQPNNGNN QFTYGVSFAS AGAGALAESF
LGMVINLGTQ LNNFKDVEKS LRSELGDAET KRVFSRAVYL FHIGANDYFY PFSANSSTFK
SNSKEKFVDF VIGNITFVIE EVYKMGGRKF GFLNVGPYEC SPNSLIRDRT KIGSCFKPVA
ELIDMHNKKF PDVLRRLQRQ LSGFRYALHD YHTSLSERIN SPSKYGFKEG KKACCGSGPL
RGINTCGNRI GPSQGYGLCE NVTDYLFYDS SHLTEKAHRQ IAELIWNGPP NVTRPYNLKA
LFELRLT
