GLIP6_ARATH
ID GLIP6_ARATH Reviewed; 362 AA.
AC Q9C996;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=GDSL esterase/lipase 6;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase 6;
DE Flags: Precursor;
GN Name=GLIP6; OrderedLocusNames=At1g71120; ORFNames=F23N20.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=16126835; DOI=10.1105/tpc.105.034819;
RA Oh I.S., Park A.R., Bae M.S., Kwon S.J., Kim Y.S., Lee J.E., Kang N.Y.,
RA Lee S., Cheong H., Park O.K.;
RT "Secretome analysis reveals an Arabidopsis lipase involved in defense
RT against Alternaria brassicicola.";
RL Plant Cell 17:2832-2847(2005).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC016972; AAG51687.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35163.1; -; Genomic_DNA.
DR PIR; G96735; G96735.
DR RefSeq; NP_177268.1; NM_105781.2.
DR AlphaFoldDB; Q9C996; -.
DR SMR; Q9C996; -.
DR STRING; 3702.AT1G71120.1; -.
DR PaxDb; Q9C996; -.
DR PRIDE; Q9C996; -.
DR ProteomicsDB; 230489; -.
DR EnsemblPlants; AT1G71120.1; AT1G71120.1; AT1G71120.
DR GeneID; 843452; -.
DR Gramene; AT1G71120.1; AT1G71120.1; AT1G71120.
DR KEGG; ath:AT1G71120; -.
DR Araport; AT1G71120; -.
DR TAIR; locus:2026286; AT1G71120.
DR eggNOG; ENOG502QQRE; Eukaryota.
DR HOGENOM; CLU_015101_0_2_1; -.
DR InParanoid; Q9C996; -.
DR OMA; LFWDEIH; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9C996; -.
DR BioCyc; ARA:AT1G71120-MON; -.
DR PRO; PR:Q9C996; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C996; baseline and differential.
DR Genevisible; Q9C996; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; ISS:TAIR.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..362
FT /note="GDSL esterase/lipase 6"
FT /id="PRO_0000367339"
FT ACT_SITE 38
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 323
FT /evidence="ECO:0000250"
FT ACT_SITE 326
FT /evidence="ECO:0000250"
FT CARBOHYD 50
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 103
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 107
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 195
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 296
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 362 AA; 40224 MW; 6CDE3EF6A33DAD98 CRC64;
MSSSSSMDLL MCLLLLISPV VLAKSSSTVP AIFTFGDSIF DAGNNHYNKN CTAQADFPPY
GSSFFHRPTG RFTNGRTVAD FISEFVGLPL QKPFLELQIQ ILNGTSNFSN GINFASAGSG
LLLDTNKFMG VTPIQTQLQQ FQTLVEQNLI EKSIIQESLF LLETGSNDIF NYFLPFRAPT
LSPDAYVNAM LDQVNKTIDQ IYKLGARRIA FFSLGPVGCV PARAMLPNAP TNKCFGKMNV
MAKMYNKRLE DIVNIIPTKY PGAIAVFGAV YGITHRFQTY PARYGFSDVS NACCGNGTLG
GLMQCGREGY KICNNPNEFL FWDFYHPTEH TYRLMSKALW NGNKNHIRPF NLMALATNKI
TF
