ALSC_ECOLI
ID ALSC_ECOLI Reviewed; 326 AA.
AC P32720; Q2M6L7;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 03-AUG-2022, entry version 158.
DE RecName: Full=D-allose transport system permease protein AlsC;
GN Name=alsC; Synonyms=yjcV; OrderedLocusNames=b4086, JW4047;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8265357; DOI=10.1093/nar/21.23.5408;
RA Blattner F.R., Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L.;
RT "Analysis of the Escherichia coli genome. IV. DNA sequence of the region
RT from 89.2 to 92.8 minutes.";
RL Nucleic Acids Res. 21:5408-5417(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-133.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=7610040; DOI=10.1093/nar/23.12.2105;
RA Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.;
RT "Analysis of the Escherichia coli genome VI: DNA sequence of the region
RT from 92.8 through 100 minutes.";
RL Nucleic Acids Res. 23:2105-2119(1995).
RN [5]
RP FUNCTION.
RX PubMed=9401019; DOI=10.1128/jb.179.24.7631-7637.1997;
RA Kim C., Song S., Park C.;
RT "The D-allose operon of Escherichia coli K-12.";
RL J. Bacteriol. 179:7631-7637(1997).
RN [6]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system AlsBAC
CC for D-allose; probably responsible for the translocation of the
CC substrate across the membrane. {ECO:0000269|PubMed:9401019}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR EMBL; U00006; AAC43180.1; -; Genomic_DNA.
DR EMBL; U14003; AAA96985.1; -; Genomic_DNA.
DR EMBL; U00096; AAC77047.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE78089.1; -; Genomic_DNA.
DR PIR; E65217; E65217.
DR RefSeq; NP_418510.1; NC_000913.3.
DR RefSeq; WP_000507106.1; NZ_SSZK01000016.1.
DR AlphaFoldDB; P32720; -.
DR BioGRID; 4262680; 9.
DR ComplexPortal; CPX-4320; D-allose ABC transporter complex.
DR STRING; 511145.b4086; -.
DR TCDB; 3.A.1.2.6; the atp-binding cassette (abc) superfamily.
DR PaxDb; P32720; -.
DR PRIDE; P32720; -.
DR EnsemblBacteria; AAC77047; AAC77047; b4086.
DR EnsemblBacteria; BAE78089; BAE78089; BAE78089.
DR GeneID; 948594; -.
DR KEGG; ecj:JW4047; -.
DR KEGG; eco:b4086; -.
DR PATRIC; fig|1411691.4.peg.2614; -.
DR EchoBASE; EB1901; -.
DR eggNOG; COG1172; Bacteria.
DR HOGENOM; CLU_028880_2_2_6; -.
DR InParanoid; P32720; -.
DR OMA; IDWQQAI; -.
DR PhylomeDB; P32720; -.
DR BioCyc; EcoCyc:YJCV-MON; -.
DR BioCyc; MetaCyc:YJCV-MON; -.
DR PRO; PR:P32720; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; ISM:EcoCyc.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015754; P:allose transmembrane transport; IC:ComplexPortal.
DR GO; GO:0015752; P:D-ribose transmembrane transport; IC:ComplexPortal.
DR InterPro; IPR001851; ABC_transp_permease.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..326
FT /note="D-allose transport system permease protein AlsC"
FT /id="PRO_0000059942"
FT TOPO_DOM 1..18
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 40..70
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 92..101
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 123..124
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 146..149
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 171..172
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 194..221
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 243..252
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 253..273
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 274..278
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 321..326
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 326 AA; 34316 MW; 996443B50BF9CF0D CRC64;
MGFTTRVKSE ASEKKPFNFA LFWDKYGTFF ILAIIVAIFG SLSPEYFLTT NNITQIFVQS
SVTVLIGMGE FFAILVAGID LSVGAILALS GMVTAKLMLA GVDPFLAAMI GGVLVGGALG
AINGCLVNWT GLHPFIITLG TNAIFRGITL VISDANSVYG FSFDFVNFFA ASVIGIPVPV
IFSLIVALIL WFLTTRMRLG RNIYALGGNK NSAFYSGIDV KFHILVVFII SGVCAGLAGV
VSTARLGAAE PLAGMGFETY AIASAIIGGT SFFGGKGRIF SVVIGGLIIG TINNGLNILQ
VQTYYQLVVM GGLIIAAVAL DRLISK
