ID   ALTA2_ALTAL             Reviewed;         190 AA.
AC   O94095;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 36.
DE   RecName: Full=Allergen Alt a 2;
DE   AltName: Allergen=Alt a 2;
GN   Name=ALTA2;
OS   Alternaria alternata (Alternaria rot fungus) (Torula alternata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Alternaria;
OC   Alternaria sect. Alternaria; Alternaria alternata complex.
OX   NCBI_TaxID=5599;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND IGE-BINDING.
RC   STRAIN=ATCC 46582 / PD 1;
RX   PubMed=10482844; DOI=10.1016/s0091-6749(99)70340-4;
RA   Bush R.K., Sanchez H., Geisler D.;
RT   "Molecular cloning of a major Alternaria alternata allergen, rAlt a 2.";
RL   J. Allergy Clin. Immunol. 104:665-671(1999).
RN   [2]
RP   ALLERGEN.
RX   PubMed=15940136; DOI=10.1016/j.jaci.2005.02.012;
RA   Asturias J.A., Ibarrola I., Ferrer A., Andreu C., Lopez-Pascual E.,
RA   Quiralte J., Florido F., Martinez A.;
RT   "Diagnosis of Alternaria alternata sensitization with natural and
RT   recombinant Alt a 1 allergens.";
RL   J. Allergy Clin. Immunol. 115:1210-1217(2005).
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC       {ECO:0000269|PubMed:15940136}.
CC   -!- CAUTION: Was originally (PubMed:10482844) identified to be a major
CC       allergen, but a second study (PubMed:15940136) reported a very low
CC       prevalence. {ECO:0000305|PubMed:10482844, ECO:0000305|PubMed:15940136}.
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DR   EMBL; U62442; AAD00097.1; -; mRNA.
DR   AlphaFoldDB; O94095; -.
DR   Allergome; 16; Alt a 2.
DR   PRIDE; O94095; -.
PE   1: Evidence at protein level;
KW   Allergen.
FT   CHAIN           1..190
FT                   /note="Allergen Alt a 2"
FT                   /id="PRO_0000345087"
SQ   SEQUENCE   190 AA;  22387 MW;  4A2867362792C72A CRC64;
     MHSSNNFFKD NIFRSLSKED PDYSRNIEGQ VIRLHWDWAQ LLMLSAKRMK VAFKLDIEKD
     QRVWDRCTAD DLKGRNGFKR CLQFTLYRPR DLLSLLNEAF FSAFRENRET IINTDLEYAA
     KSISMARLED LWKEYQKIFP SIQVITSAFR SIEPELTVYT CLKKIEASFE LIEENGDPKI
     TSEIQLLKAS