ALX_PHOLL
ID ALX_PHOLL Reviewed; 320 AA.
AC P60067; Q7N0A1;
DT 28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2003, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Putative membrane-bound redox modulator Alx;
GN Name=alx; OrderedLocusNames=plu3992;
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01;
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- FUNCTION: Has been proposed to be a redox modulator.
CC {ECO:0000250|UniProtKB:P42601}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P42601}; Multi-pass membrane protein
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TerC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX571872; CAE16364.1; -; Genomic_DNA.
DR RefSeq; WP_011148124.1; NC_005126.1.
DR AlphaFoldDB; P60067; -.
DR EnsemblBacteria; CAE16364; CAE16364; plu3992.
DR GeneID; 24169203; -.
DR KEGG; plu:plu3992; -.
DR eggNOG; COG0861; Bacteria.
DR HOGENOM; CLU_045644_1_2_6; -.
DR OMA; ADHAREY; -.
DR OrthoDB; 1917125at2; -.
DR BioCyc; PLUM243265:PLU_RS19785-MON; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR005496; Integral_membrane_TerC.
DR InterPro; IPR022369; Integral_membrane_TerC_rswitch.
DR PANTHER; PTHR30238:SF0; PTHR30238:SF0; 1.
DR Pfam; PF03741; TerC; 1.
DR TIGRFAMs; TIGR03718; R_switched_Alx; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..320
FT /note="Putative membrane-bound redox modulator Alx"
FT /id="PRO_0000103413"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 271..291
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 320 AA; 35703 MW; 1C21036A5CECBFCB CRC64;
MNSVGSPLLW GSFAVLITIM LLLDLSLQGR KKEQAMSFRQ AAVWSVIWVS LSLLFALGLW
WYCRETVGVA VANSQVMAFL TGYLLEKALA VDNVFVWLML FSYFAIPANL QRRVLIYGVL
GAIVLRTVMI FAGSWLVSQF SWILYLFGLF LLVTGVKMAL VKEDDSPIGD KPFVRWLKAH
IRITDNLHGE RFFVKEKGLL YATPLILVLI LVEISDVIFA VDSIPAIFAV TTDPFIVLTS
NLFAILGLRA MYFLLAGVAE KFTMLKYGLS VILAFIGIKM LIIDFYHIPI GGSLGAVASI
LAVTMIINVW VNKYKATENQ
