ID   ALY1_SCHPO              Reviewed;         504 AA.
AC   Q8WZK5;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2016, sequence version 2.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Putative arrestin-related trafficking adapter SPBC839.02;
GN   ORFNames=SPBC839.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   GENE MODEL REVISION.
RX   PubMed=24929437; DOI=10.1038/nsmb.2843;
RA   Duncan C.D., Mata J.;
RT   "The translational landscape of fission-yeast meiosis and sporulation.";
RL   Nat. Struct. Mol. Biol. 21:641-647(2014).
CC   -!- FUNCTION: May regulate endocytosis in response to extracellular
CC       stimuli. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ALY1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAB46695.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CU329671; CAB46695.1; ALT_SEQ; Genomic_DNA.
DR   PIR; T40709; T40709.
DR   RefSeq; NP_595242.1; NM_001021148.2.
DR   AlphaFoldDB; Q8WZK5; -.
DR   BioGRID; 277719; 29.
DR   STRING; 4896.SPBC839.02.1; -.
DR   iPTMnet; Q8WZK5; -.
DR   PaxDb; Q8WZK5; -.
DR   PRIDE; Q8WZK5; -.
DR   EnsemblFungi; SPBC839.02.1; SPBC839.02.1:pep; SPBC839.02.
DR   GeneID; 2541205; -.
DR   KEGG; spo:SPBC839.02; -.
DR   PomBase; SPBC839.02; -.
DR   VEuPathDB; FungiDB:SPBC839.02; -.
DR   eggNOG; KOG3780; Eukaryota.
DR   HOGENOM; CLU_008578_0_1_1; -.
DR   InParanoid; Q8WZK5; -.
DR   Reactome; R-SPO-844456; The NLRP3 inflammasome.
DR   PRO; PR:Q8WZK5; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; ISM:PomBase.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   GO; GO:0072583; P:clathrin-dependent endocytosis; ISO:PomBase.
DR   GO; GO:0015031; P:protein transport; IBA:GO_Central.
DR   GO; GO:0070086; P:ubiquitin-dependent endocytosis; IBA:GO_Central.
DR   Gene3D; 2.60.40.640; -; 1.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR014756; Ig_E-set.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   Pfam; PF00339; Arrestin_N; 1.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..504
FT                   /note="Putative arrestin-related trafficking adapter
FT                   SPBC839.02"
FT                   /id="PRO_0000353798"
FT   REGION          481..504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   504 AA;  57931 MW;  1DE5F7CDCF5374AF CRC64;
     MYIPNLRNYH DKVFPYGPSS NGYNPVIRLT DRTTQPDPSQ HIYQEEKISK CEGLSYRARE
     WLLLSSNSNA RVAIALAEPV LYLPGATSSE IQSEHSAVLR GSLCIQIYKP VKLKKIQLSF
     KGKSRTEWPE GIPPKLFDTY EENSIMNHCW VFFHSEQKVD ENSHGAVWYK VLPHYADTAH
     YPRSMECFYP GEYVYNFELP ISCTYPESIQ TDMGRVYYFL ETLVDRSSTF SGKSTGRIPI
     ELIRSPCSTS VATSEPILVS KSWEDRLHYE VQVGEKCVVM GQVVPVNFKF TLLGEVKFHK
     LRLFLMERRY YYCRQRSVRR KEKTRQLLLY ERSAPKNQCL LSDWKQVRPD VYELSDQVRI
     PGCHDMAANI VHFDTTYPNI KITHTVRTVL RFSCENSPEL MGSAKYLEIY IDSPVRLLSC
     RCSDGSTMLP AYCPIIPSSE VNFCSIDNRI IAGMNRDLAL DSDIIGNSPP SFDSWTAVPY
     QAPPPKYDDI FQSGSSHDEN HDDN