ID   ALYS_MYCPH              Reviewed;          17 AA.
AC   P81528;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=38 kDa autolysin;
DE            EC=3.2.1.-;
DE   AltName: Full=Beta-glycosidase;
DE   AltName: Full=Peptidoglycan hydrolase;
DE   Flags: Fragment;
GN   Name=lytA;
OS   Mycolicibacterium phlei (Mycobacterium phlei).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=1771;
RN   [1]
RP   PROTEIN SEQUENCE, AND CHARACTERIZATION.
RC   STRAIN=425;
RX   PubMed=10206696; DOI=10.1099/13500872-145-1-169;
RA   Li Z.S., Beveridge T.J., Betts J., Clarke A.J.;
RT   "Partial characterization of a major autolysin from Mycobacterium phlei.";
RL   Microbiology 145:169-176(1999).
CC   -!- FUNCTION: Hydrolyzes the cell walls of mycobacteria. May play an
CC       important role in cell wall growth and cell separation.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Optimum pH is 7.5.;
CC   -!- SUBUNIT: Monomer.
CC   -!- PTM: The N-terminus is blocked. {ECO:0000305}.
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DR   AlphaFoldDB; P81528; -.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antimicrobial; Bacteriolytic enzyme; Cell cycle; Cell division;
KW   Cell wall biogenesis/degradation; Direct protein sequencing; Glycosidase;
KW   Hydrolase; Septation.
FT   CHAIN           <1..>17
FT                   /note="38 kDa autolysin"
FT                   /id="PRO_0000064574"
FT   UNSURE          1..2
FT                   /note="VA or AV or IG or LG or GI or GL"
FT   UNSURE          14
FT                   /note="I or L"
FT   NON_TER         1
FT   NON_TER         17
SQ   SEQUENCE   17 AA;  1817 MW;  1FACA3240F5C4EC5 CRC64;
     VAVKATTTEE ETEIPAK