AM1_ORYSJ
ID AM1_ORYSJ Reviewed; 803 AA.
AC Q53KW9;
DT 20-JUN-2018, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Protein AMEIOTIC 1 homolog {ECO:0000303|PubMed:21221128};
DE Short=OsAM1 {ECO:0000303|PubMed:21221128};
GN Name=AM1 {ECO:0000303|PubMed:21221128};
GN OrderedLocusNames=Os03g0650400 {ECO:0000312|EMBL:BAF12699.1},
GN LOC_Os03g44760 {ECO:0000312|EMBL:ABF97914.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, AND MUTAGENESIS OF ARG-360.
RC STRAIN=cv. Wuxiangjing 9;
RX PubMed=21221128; DOI=10.1038/cr.2011.7;
RA Che L., Tang D., Wang K., Wang M., Zhu K., Yu H., Gu M., Cheng Z.;
RT "OsAM1 is required for leptotene-zygotene transition in rice.";
RL Cell Res. 21:654-665(2011).
CC -!- FUNCTION: Plays a fundamental role in building the proper chromosome
CC structure at the beginning of meiosis in male meiocytes. Required for
CC the transition from leptotene to zygotene in meiocytes. Required for
CC homologous chromosome pairing. {ECO:0000269|PubMed:21221128}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21221128}.
CC Chromosome. Note=Diffuse localization in the nucleus during the
CC initiation of meiosis. Binds to chromatin in early meiotic prophase I.
CC {ECO:0000269|PubMed:21221128}.
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DR EMBL; AC145381; AAX95530.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF97914.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF12699.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS85511.1; -; Genomic_DNA.
DR RefSeq; XP_015631380.1; XM_015775894.1.
DR AlphaFoldDB; Q53KW9; -.
DR SMR; Q53KW9; -.
DR STRING; 4530.OS03T0650400-02; -.
DR PaxDb; Q53KW9; -.
DR PRIDE; Q53KW9; -.
DR EnsemblPlants; Os03t0650400-02; Os03t0650400-02; Os03g0650400.
DR GeneID; 4333586; -.
DR Gramene; Os03t0650400-02; Os03t0650400-02; Os03g0650400.
DR KEGG; osa:4333586; -.
DR eggNOG; ENOG502QU2W; Eukaryota.
DR InParanoid; Q53KW9; -.
DR OMA; KFLGRHE; -.
DR OrthoDB; 652033at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR ExpressionAtlas; Q53KW9; baseline and differential.
DR GO; GO:0005694; C:chromosome; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0051321; P:meiotic cell cycle; IMP:UniProtKB.
DR GO; GO:0051177; P:meiotic sister chromatid cohesion; IEA:InterPro.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IEA:InterPro.
DR InterPro; IPR044221; DYAD/AMEIOTIC1.
DR PANTHER; PTHR46740; PTHR46740; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Chromosome; Chromosome partition; Coiled coil;
KW Meiosis; Nucleus; Reference proteome.
FT CHAIN 1..803
FT /note="Protein AMEIOTIC 1 homolog"
FT /id="PRO_0000444505"
FT REGION 21..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 450..567
FT /evidence="ECO:0000255"
FT COMPBIAS 35..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..310
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MUTAGEN 360
FT /note="R->W: In Osam1-1; sterile phenotype due to male
FT meiosis arrested at leptotene."
FT /evidence="ECO:0000269|PubMed:21221128"
SQ SEQUENCE 803 AA; 88270 MW; 34C045C6792FD005 CRC64;
MDAEMAAPAL AAAHLLDSPM RPQVSRYYSK KRGSSHSRNG KDDANHDESK NQSPGLPLSR
QSLSSSATHT YHTGGFYEID HEKLPPKSPI HLKSIRVVKV SGYTSLDVTV SFPSLLALRS
FFSSSPRSCT GPELDERFVM SSNHAARILR RRVAEEELAG DVMHQDSFWL VKPCLYDFSA
SSPHDVLTPS PPPATAQAKA PAASSCLLDT LKCDGAGWGV RRRVRYIGRH HDASKEASAA
SLDGYNTEVS VQEEQQQRLR LRLRLRQRRE QEDNKSTSNG KRKREEAESS MDKSRAARKK
KAKTYKSPKK VEKRRVVEAK DGDPRRGKDR WSAERYAAAE RSLLDIMRSH GACFGAPVMR
QALREEARKH IGDTGLLDHL LKHMAGRVPE GSADRFRRRH NADGAMEYWL EPAELAEVRR
LAGVSDPYWV PPPGWKPGDD VSAVAGDLLV KKKVEELAEE VDGVKRHIEQ LSSNLVQLEK
ETKSEAERSY SSRKEKYQKL MKANEKLEKQ VLSMKDMYEH LVQKKGKLKK EVLSLKDKYK
LVLEKNDKLE EQMASLSSSF LSLKEQLLLP RNGDNLNMER ERVEVTLGKQ EGLVPGEPLY
VDGGDRISQQ ADATVVQVGE KRTARKSSFR ICKPQGTFMW PHMASGTSMA ISGGGSSSCP
VASGPEQLPR SSSCPSIGPG GLPPSSRAPA EVVVASPLDE HVAFRGGFNT PPSASSTNAA
AAAKLPPLPS PTSPLQTRAL FAAGFTVPAL HNFSGLTLRH VDSSSPSSAP CGAREKMVTL
FDGDCRGISV VGTELALATP SYC
