GLNP_ECO57
ID GLNP_ECO57 Reviewed; 219 AA.
AC P0AEQ8; P10345; P76825;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Glutamine transport system permease protein GlnP;
GN Name=glnP; OrderedLocusNames=Z1032, ECs0888;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC glutamine; probably responsible for the translocation of the substrate
CC across the membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- INDUCTION: By lack of glutamine. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. HisMQ subfamily. {ECO:0000305}.
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DR EMBL; AE005174; AAG55182.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB34311.1; -; Genomic_DNA.
DR PIR; B85590; B85590.
DR PIR; H90739; H90739.
DR RefSeq; NP_308915.1; NC_002695.1.
DR RefSeq; WP_001159065.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P0AEQ8; -.
DR SMR; P0AEQ8; -.
DR STRING; 155864.EDL933_0933; -.
DR EnsemblBacteria; AAG55182; AAG55182; Z1032.
DR EnsemblBacteria; BAB34311; BAB34311; ECs_0888.
DR GeneID; 66670918; -.
DR GeneID; 917627; -.
DR KEGG; ece:Z1032; -.
DR KEGG; ecs:ECs_0888; -.
DR PATRIC; fig|386585.9.peg.1002; -.
DR eggNOG; COG0765; Bacteria.
DR HOGENOM; CLU_019602_1_0_6; -.
DR OMA; IGLHYST; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR010065; AA_ABC_transptr_permease_3TM.
DR InterPro; IPR043429; ArtM/GltK/GlnP/TcyL/YhdX-like.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR30614; PTHR30614; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR TIGRFAMs; TIGR01726; HEQRo_perm_3TM; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..219
FT /note="Glutamine transport system permease protein GlnP"
FT /id="PRO_0000060031"
FT TOPO_DOM 1..22
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 44..53
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 75..88
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 110..150
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 172..187
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 209..219
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 19..209
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 219 AA; 24364 MW; 20A94A31BE02121C CRC64;
MQFDWSAIWP AIPLLIEGAK MTLWISVLGL AGGLVIGLLA GFARTFGGWI ANHVALVFIE
VIRGTPIVVQ VMFIYFALPM AFNDLRIDPF TAAVVTIMIN SGAYIAEITR GAVLSIHKGF
REAGLALGLS RWETIRYVIL PLALRRMLPP LGNQWIISIK DTSLFIVIGV AELTRQGQEI
IAGNFRALEI WSAVAVFYLI ITLVLSFILR RLERRMKIL
