ID   GLNT2_ALIF1             Reviewed;         388 AA.
AC   Q5E5M9;
DT   05-JUL-2017, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Glutamine transporter 2 {ECO:0000305};
GN   OrderedLocusNames=VF_1172 {ECO:0000312|EMBL:AAW85667.1};
OS   Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Aliivibrio.
OX   NCBI_TaxID=312309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700601 / ES114;
RX   PubMed=15703294; DOI=10.1073/pnas.0409900102;
RA   Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R.,
RA   Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E.,
RA   Stevens A., Visick K., Whistler C., Greenberg E.P.;
RT   "Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with
RT   pathogenic congeners.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
RN   [2]
RP   FUNCTION.
RC   STRAIN=ATCC 700601 / ES114;
RX   PubMed=28446608; DOI=10.1074/jbc.m116.763193;
RA   Pan S., Nikolakakis K., Adamczyk P.A., Pan M., Ruby E.G., Reed J.L.;
RT   "Model-enabled gene search (MEGS) allows fast and direct discovery of
RT   enzymatic and transport gene functions in the marine bacterium Vibrio
RT   fischeri.";
RL   J. Biol. Chem. 292:10250-10261(2017).
CC   -!- FUNCTION: Seems to be involved in glutamine transport. Complements an
CC       E. coli glnP deletion mutant. {ECO:0000269|PubMed:28446608}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       {ECO:0000305}.
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DR   EMBL; CP000020; AAW85667.1; -; Genomic_DNA.
DR   RefSeq; WP_011261794.1; NC_006840.2.
DR   RefSeq; YP_204555.1; NC_006840.2.
DR   AlphaFoldDB; Q5E5M9; -.
DR   SMR; Q5E5M9; -.
DR   STRING; 312309.VF_1172; -.
DR   EnsemblBacteria; AAW85667; AAW85667; VF_1172.
DR   KEGG; vfi:VF_1172; -.
DR   PATRIC; fig|312309.11.peg.1179; -.
DR   eggNOG; COG0814; Bacteria.
DR   HOGENOM; CLU_038102_3_0_6; -.
DR   OMA; FSAKNEY; -.
DR   OrthoDB; 935253at2; -.
DR   Proteomes; UP000000537; Chromosome I.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0015173; F:aromatic amino acid transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR018227; Amino_acid_transport_2.
DR   InterPro; IPR013059; Trp_tyr_transpt.
DR   PANTHER; PTHR46997; PTHR46997; 1.
DR   Pfam; PF03222; Trp_Tyr_perm; 1.
DR   PRINTS; PR00166; AROAAPRMEASE.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..388
FT                   /note="Glutamine transporter 2"
FT                   /id="PRO_0000440878"
FT   TRANSMEM        5..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        268..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        326..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   388 AA;  42367 MW;  230F2EA5CC4D8741 CRC64;
     MNFKLFGSAL ILSGTALGAG MLAIPMVLAQ FGLFYSTLLM LIICAGTTYA ALLLTEACSK
     TELAFGINTV ANKTIGKGGQ LVTNALFYLL LFCMLIAYIL GAADLIKRIF SMMNVEMSIE
     FAQVAFTLFA SAFVVCGTQI IDKLNRLLFF FMISMLVLTL IILIPGMTVE NLSQVTNHDK
     GMLFDTSTIL FTSFASMPVI PSLVAYNKEA TKQQLRNMVI LGSIIPLICY LVWLYAVVGN
     LTANEITHFS NISDLIQTFS AKNEYIEIIL SIFTSLALLT SFLGVAMALY NQNKDMISHN
     KIVTYVCTFI LPLLGAGLAA DQFLSVLGYA GVILVFLAIF IPLAMVVTLR KKETEEVHQN
     LHIYTAEGGK LALGLTLLFG LLLLISQI