ID   GLOB_ANTMA              Reviewed;         215 AA.
AC   Q03378;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Floral homeotic protein GLOBOSA;
GN   Name=GLO;
OS   Antirrhinum majus (Garden snapdragon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Plantaginaceae; Antirrhineae; Antirrhinum.
OX   NCBI_TaxID=4151;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1361166; DOI=10.1002/j.1460-2075.1992.tb05574.x;
RA   Troebner W., Ramirez L., Motte P., Hue I., Huijser P., Loennig W.-E.,
RA   Saedler H., Sommer H., Schwartz-Sommer Z.;
RT   "GLOBOSA: a homeotic gene which interacts with DEFICIENS in the control of
RT   Antirrhinum floral organogenesis.";
RL   EMBO J. 11:4693-4704(1992).
CC   -!- FUNCTION: Transcription factor involved in the genetic control of
CC       flower development. Acts in conjunction with DEFICIENS (defA).
CC   -!- INTERACTION:
CC       Q03378; P23706: DEFA; NbExp=6; IntAct=EBI-633469, EBI-633463;
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- MISCELLANEOUS: Mutations in Glo cause transformation of petals into
CC       sepals and stamina into carpels.
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DR   EMBL; X68831; CAA48725.1; -; Genomic_DNA.
DR   PIR; S28062; S28062.
DR   AlphaFoldDB; Q03378; -.
DR   SMR; Q03378; -.
DR   IntAct; Q03378; 1.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; -; 1.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002487; TF_Kbox.
DR   InterPro; IPR002100; TF_MADSbox.
DR   InterPro; IPR036879; TF_MADSbox_sf.
DR   Pfam; PF01486; K-box; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SSF55455; 1.
DR   PROSITE; PS51297; K_BOX; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   1: Evidence at protein level;
KW   Activator; Developmental protein; DNA-binding; Nucleus; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..215
FT                   /note="Floral homeotic protein GLOBOSA"
FT                   /id="PRO_0000199455"
FT   DOMAIN          3..57
FT                   /note="MADS-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT   DOMAIN          84..170
FT                   /note="K-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
SQ   SEQUENCE   215 AA;  25363 MW;  0DE2A3E37815B7E4 CRC64;
     MGRGKIEIKR IENSSNRQVT YSKRRNGIMK KAKEISVLCD AHVSVIIFAS SGKMHEFCSP
     STTLVDMLDH YHKLSGKRLW DPKHEHLDNE INRVKKENDS MQIELRHLKG EDITTLNYKE
     LMVLEDALEN GTSALKNKQM EFVRMMRKHN EMVEEENQSL QFKLRQMHLD PMNDNVMESQ
     AVYDHHHHQN IADYEAQMPF AFRVQPMQPN LQERF