ID   GLOB_TOBAC              Reviewed;         209 AA.
AC   Q03416;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Floral homeotic protein GLOBOSA;
GN   Name=GLO;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. SR1; TISSUE=Flower;
RX   PubMed=8099711; DOI=10.1007/bf00281633;
RA   Hansen G., Estruch J.J., Sommer H., Spena A.;
RT   "NTGLO: a tobacco homologue of the GLOBOSA floral homeotic gene of
RT   Antirrhinum majus: cDNA sequence and expression pattern.";
RL   Mol. Gen. Genet. 239:310-312(1993).
CC   -!- FUNCTION: Transcription factor involved in the genetic control of
CC       flower development. Acts in conjunction with DEFICIENS (defA).
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- TISSUE SPECIFICITY: Expressed mainly in floral organs and, within the
CC       flower, expression is restricted to petals and stamens.
CC   -!- MISCELLANEOUS: Mutations in Glo cause transformation of petals into
CC       sepals and stamina into carpels.
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DR   EMBL; X67959; CAA48142.1; -; mRNA.
DR   PIR; S35226; S35226.
DR   RefSeq; NP_001313154.1; NM_001326225.1.
DR   AlphaFoldDB; Q03416; -.
DR   SMR; Q03416; -.
DR   STRING; 4097.Q03416; -.
DR   GeneID; 107829524; -.
DR   KEGG; nta:107829524; -.
DR   OMA; MFRRNDK; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; -; 1.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002487; TF_Kbox.
DR   InterPro; IPR002100; TF_MADSbox.
DR   InterPro; IPR036879; TF_MADSbox_sf.
DR   Pfam; PF01486; K-box; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SSF55455; 1.
DR   PROSITE; PS51297; K_BOX; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   2: Evidence at transcript level;
KW   Activator; Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..209
FT                   /note="Floral homeotic protein GLOBOSA"
FT                   /id="PRO_0000199456"
FT   DOMAIN          3..57
FT                   /note="MADS-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT   DOMAIN          82..173
FT                   /note="K-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
SQ   SEQUENCE   209 AA;  24691 MW;  5661F9C1640E1A47 CRC64;
     MGRGKIEIKR IENSSNRQVT YSKRRNGILK KAKEISVLCD ARVSVIIFAS SGKMHEFSST
     SLVDILDQYH KLTGRRLWDA KHENLDNEIN KVKKDNDNMQ IELRHLKGED ITSLNHRELM
     MLEDALDNGL TSIRNKQNDL LRMMRKKTQS MEEEQDQLNW QLRQLEIASM NRNMGEIGEV
     FHQRENEYQT QMPFAFRVQP MQPNLQERF