GLOD5_MOUSE
ID GLOD5_MOUSE Reviewed; 148 AA.
AC Q9D8I3;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Glyoxalase domain-containing protein 5;
GN Name=Glod5;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Small intestine;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Kidney;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the glyoxalase I family. {ECO:0000305}.
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DR EMBL; AK008008; BAB25406.1; -; mRNA.
DR EMBL; AL670169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC061027; AAH61027.1; -; mRNA.
DR CCDS; CCDS29982.1; -.
DR RefSeq; NP_081503.1; NM_027227.2.
DR AlphaFoldDB; Q9D8I3; -.
DR SMR; Q9D8I3; -.
DR STRING; 10090.ENSMUSP00000033503; -.
DR iPTMnet; Q9D8I3; -.
DR PhosphoSitePlus; Q9D8I3; -.
DR jPOST; Q9D8I3; -.
DR MaxQB; Q9D8I3; -.
DR PaxDb; Q9D8I3; -.
DR PeptideAtlas; Q9D8I3; -.
DR PRIDE; Q9D8I3; -.
DR ProteomicsDB; 267729; -.
DR Antibodypedia; 546; 13 antibodies from 8 providers.
DR DNASU; 69824; -.
DR Ensembl; ENSMUST00000033503; ENSMUSP00000033503; ENSMUSG00000031163.
DR GeneID; 69824; -.
DR KEGG; mmu:69824; -.
DR UCSC; uc009snn.1; mouse.
DR CTD; 392465; -.
DR MGI; MGI:1917074; Glod5.
DR VEuPathDB; HostDB:ENSMUSG00000031163; -.
DR eggNOG; ENOG502RZMP; Eukaryota.
DR GeneTree; ENSGT00940000153941; -.
DR HOGENOM; CLU_046006_4_3_1; -.
DR InParanoid; Q9D8I3; -.
DR OMA; PPPCFIQ; -.
DR OrthoDB; 1456521at2759; -.
DR PhylomeDB; Q9D8I3; -.
DR TreeFam; TF300075; -.
DR BioGRID-ORCS; 69824; 1 hit in 72 CRISPR screens.
DR PRO; PR:Q9D8I3; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q9D8I3; protein.
DR Bgee; ENSMUSG00000031163; Expressed in small intestine Peyer's patch and 42 other tissues.
DR Genevisible; Q9D8I3; MM.
DR Gene3D; 3.10.180.10; -; 1.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR InterPro; IPR037523; VOC.
DR Pfam; PF00903; Glyoxalase; 1.
DR SUPFAM; SSF54593; SSF54593; 1.
DR PROSITE; PS51819; VOC; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..148
FT /note="Glyoxalase domain-containing protein 5"
FT /id="PRO_0000305327"
FT DOMAIN 25..145
FT /note="VOC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01163"
SQ SEQUENCE 148 AA; 16595 MW; 43C2A44F8870D86A CRC64;
MCDPTSESQL WRSSSQIPSP CLICRLDHIV MTVKNIEDTT MFYSKILGME VTTFKGNRKA
LCFGDQKFNL HEVGKEFDPK AAHPVPGSLD VCLITEAPLE EVIERLKAFD VPIEEGPVFR
TGAKGPILSI YFRDPDRNLL EVSSYVTS
