GLPB_PANTR
ID GLPB_PANTR Reviewed; 123 AA.
AC Q28914;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Glycophorin-B;
DE AltName: CD_antigen=CD235b;
DE Flags: Precursor;
GN Name=GYPB; Synonyms=GPB;
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=7563135; DOI=10.1007/bf00160319;
RA Huang C.-H., Xie S.S., Socha W., Blumenfeld O.O.;
RT "Sequence diversification and exon inactivation in the glycophorin A gene
RT family from chimpanzee to human.";
RL J. Mol. Evol. 41:478-486(1995).
CC -!- FUNCTION: This protein is a minor sialoglycoprotein in erythrocyte
CC membranes.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane
CC protein.
CC -!- PTM: The N-terminal extracellular domain is heavily glycosylated on
CC serine and threonine residues. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the glycophorin-A family. {ECO:0000305}.
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DR EMBL; S79726; AAB35339.1; -; mRNA.
DR AlphaFoldDB; Q28914; -.
DR SMR; Q28914; -.
DR eggNOG; ENOG502TKYQ; Eukaryota.
DR InParanoid; Q28914; -.
DR Proteomes; UP000002277; Unplaced.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR InterPro; IPR001195; Glycophorin.
DR InterPro; IPR018938; Glycophorin_CS.
DR PANTHER; PTHR13813; PTHR13813; 1.
DR PIRSF; PIRSF002466; Glycophorin; 1.
DR PROSITE; PS00312; GLYCOPHORIN_A; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; Membrane; Reference proteome; Sialic acid;
KW Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..19
FT /evidence="ECO:0000250"
FT CHAIN 20..123
FT /note="Glycophorin-B"
FT /id="PRO_0000012137"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 123 AA; 13246 MW; 627923F06B60BB7A CRC64;
MYGKIIFVLL LSEIVSISAS STTEVAMHTS TSSSVTKSYI SSQTNDKHKG DTYPATLGAH
EVSEISVTTV YPPEEDNGEW VQPVHPFSRP APVVIILIIL CVMAGVIGTI LLISYGIRLL
IKA