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GLPB_PANTR
ID   GLPB_PANTR              Reviewed;         123 AA.
AC   Q28914;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Glycophorin-B;
DE   AltName: CD_antigen=CD235b;
DE   Flags: Precursor;
GN   Name=GYPB; Synonyms=GPB;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=7563135; DOI=10.1007/bf00160319;
RA   Huang C.-H., Xie S.S., Socha W., Blumenfeld O.O.;
RT   "Sequence diversification and exon inactivation in the glycophorin A gene
RT   family from chimpanzee to human.";
RL   J. Mol. Evol. 41:478-486(1995).
CC   -!- FUNCTION: This protein is a minor sialoglycoprotein in erythrocyte
CC       membranes.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane
CC       protein.
CC   -!- PTM: The N-terminal extracellular domain is heavily glycosylated on
CC       serine and threonine residues. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycophorin-A family. {ECO:0000305}.
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DR   EMBL; S79726; AAB35339.1; -; mRNA.
DR   AlphaFoldDB; Q28914; -.
DR   SMR; Q28914; -.
DR   eggNOG; ENOG502TKYQ; Eukaryota.
DR   InParanoid; Q28914; -.
DR   Proteomes; UP000002277; Unplaced.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   InterPro; IPR001195; Glycophorin.
DR   InterPro; IPR018938; Glycophorin_CS.
DR   PANTHER; PTHR13813; PTHR13813; 1.
DR   PIRSF; PIRSF002466; Glycophorin; 1.
DR   PROSITE; PS00312; GLYCOPHORIN_A; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; Membrane; Reference proteome; Sialic acid;
KW   Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000250"
FT   CHAIN           20..123
FT                   /note="Glycophorin-B"
FT                   /id="PRO_0000012137"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   123 AA;  13246 MW;  627923F06B60BB7A CRC64;
     MYGKIIFVLL LSEIVSISAS STTEVAMHTS TSSSVTKSYI SSQTNDKHKG DTYPATLGAH
     EVSEISVTTV YPPEEDNGEW VQPVHPFSRP APVVIILIIL CVMAGVIGTI LLISYGIRLL
     IKA
 
 
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