ID   GLPC_RAT                Reviewed;          95 AA.
AC   Q6XFR6;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Glycophorin-C;
DE   AltName: CD_antigen=CD236;
GN   Name=Gypc;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Chen Y., Peng J., Huang C.-H.;
RT   "Sequence and evolution of glycophorin C (GPC) proteins.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [4]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-78, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type III
CC       membrane protein {ECO:0000250}. Note=Linked to the membrane via band
CC       4.1. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycophorin-C family. {ECO:0000305}.
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DR   EMBL; AY234182; AAP70023.1; -; mRNA.
DR   EMBL; CH473974; EDL76190.1; -; Genomic_DNA.
DR   EMBL; BC103641; AAI03642.1; -; mRNA.
DR   RefSeq; NP_001013251.1; NM_001013233.1.
DR   AlphaFoldDB; Q6XFR6; -.
DR   SMR; Q6XFR6; -.
DR   STRING; 10116.ENSRNOP00000049537; -.
DR   iPTMnet; Q6XFR6; -.
DR   PhosphoSitePlus; Q6XFR6; -.
DR   PaxDb; Q6XFR6; -.
DR   PRIDE; Q6XFR6; -.
DR   Ensembl; ENSRNOT00000046369; ENSRNOP00000049537; ENSRNOG00000029939.
DR   GeneID; 364837; -.
DR   KEGG; rno:364837; -.
DR   UCSC; RGD:1310295; rat.
DR   CTD; 2995; -.
DR   RGD; 1310295; Gypc.
DR   eggNOG; ENOG502S5JS; Eukaryota.
DR   GeneTree; ENSGT00510000049102; -.
DR   HOGENOM; CLU_176666_0_0_1; -.
DR   InParanoid; Q6XFR6; -.
DR   OMA; QPHGDVE; -.
DR   OrthoDB; 1623675at2759; -.
DR   PhylomeDB; Q6XFR6; -.
DR   TreeFam; TF337016; -.
DR   PRO; PR:Q6XFR6; -.
DR   Proteomes; UP000002494; Chromosome 18.
DR   Proteomes; UP000234681; Chromosome 18.
DR   Bgee; ENSRNOG00000029939; Expressed in heart and 19 other tissues.
DR   Genevisible; Q6XFR6; RN.
DR   GO; GO:0030863; C:cortical cytoskeleton; ISO:RGD.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; ISO:RGD.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR042192; Glycophorin-C.
DR   InterPro; IPR003585; Neurexin-like.
DR   PANTHER; PTHR47614; PTHR47614; 1.
DR   SMART; SM00294; 4.1m; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..95
FT                   /note="Glycophorin-C"
FT                   /id="PRO_0000378455"
FT   TOPO_DOM        1..25
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..46
FT                   /note="Helical; Signal-anchor for type III membrane
FT                   protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        47..95
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         71
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P04921"
FT   MOD_RES         78
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         89
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P04921"
SQ   SEQUENCE   95 AA;  10443 MW;  6917EF24507EC340 CRC64;
     MSSPVRTPPP ERLEPNPGMS YAVMEIAIIA AVITAVALVL VCLLFLMLRY LYRHKGTYYT
     NEAKGTEFAE SADAALQSDP ALQDAGDTSK KEYFI