ID   GLPE_PANTR              Reviewed;          78 AA.
AC   Q28915;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Glycophorin-E;
DE   Flags: Precursor;
GN   Name=GYPE; Synonyms=GPE;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=7563135; DOI=10.1007/bf00160319;
RA   Huang C.-H., Xie S.S., Socha W., Blumenfeld O.O.;
RT   "Sequence diversification and exon inactivation in the glycophorin A gene
RT   family from chimpanzee to human.";
RL   J. Mol. Evol. 41:478-486(1995).
CC   -!- FUNCTION: This protein is a minor sialoglycoprotein in erythrocyte
CC       membranes.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
CC   -!- PTM: The N-terminal extracellular domain is heavily glycosylated on
CC       serine and threonine residues. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycophorin-A family. {ECO:0000305}.
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DR   EMBL; S79727; AAB35340.1; -; mRNA.
DR   RefSeq; XP_001140551.4; XM_001140551.5.
DR   AlphaFoldDB; Q28915; -.
DR   SMR; Q28915; -.
DR   InParanoid; Q28915; -.
DR   Proteomes; UP000002277; Unplaced.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   InterPro; IPR001195; Glycophorin.
DR   PANTHER; PTHR13813; PTHR13813; 2.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Sialic acid; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000250"
FT   CHAIN           20..78
FT                   /note="Glycophorin-E"
FT                   /id="PRO_0000012139"
FT   TOPO_DOM        20..51
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        73..78
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   78 AA;  8366 MW;  E815735BAB3C7E70 CRC64;
     MYGKIIFVLL LSAIVSISAS STTGVAMHTS TSSSVTKSYI SSQINALVEK ILIILCPMAG
     VIGMILLIYY SIRRLIKA