GLPG_CROS8
ID GLPG_CROS8 Reviewed; 276 AA.
AC A7MGE5;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Rhomboid protease GlpG homolog;
GN Name=glpG; OrderedLocusNames=ESA_04318;
OS Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Cronobacter.
OX NCBI_TaxID=290339;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-894;
RX PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA McClelland M., Forsythe S.J.;
RT "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT hybridization analysis with other Cronobacter species.";
RL PLoS ONE 5:E9556-E9556(2010).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the peptidase S54 family. {ECO:0000305}.
CC -!- CAUTION: Although strongly related to the peptidase S54 family, it
CC lacks the conserved active sites, suggesting that it has no peptidase
CC activity. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000783; ABU79497.1; -; Genomic_DNA.
DR RefSeq; WP_007899829.1; NC_009778.1.
DR AlphaFoldDB; A7MGE5; -.
DR SMR; A7MGE5; -.
DR EnsemblBacteria; ABU79497; ABU79497; ESA_04318.
DR GeneID; 56732919; -.
DR KEGG; esa:ESA_04318; -.
DR HOGENOM; CLU_058989_0_0_6; -.
DR OMA; LLGHCWI; -.
DR OrthoDB; 2053476at2; -.
DR Proteomes; UP000000260; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 1.20.1540.10; -; 1.
DR Gene3D; 3.30.70.2350; -; 1.
DR InterPro; IPR038236; GlpG_N_sf.
DR InterPro; IPR022732; Peptidase_S54_GlpG_N.
DR InterPro; IPR022764; Peptidase_S54_rhomboid_dom.
DR InterPro; IPR035952; Rhomboid-like_sf.
DR InterPro; IPR023662; Rhomboid_protease_GlpG.
DR Pfam; PF01694; Rhomboid; 1.
DR Pfam; PF12122; Rhomboid_N; 1.
DR SUPFAM; SSF144091; SSF144091; 1.
DR TIGRFAMs; TIGR04239; rhombo_GlpG; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..276
FT /note="Rhomboid protease GlpG homolog"
FT /id="PRO_0000321676"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 276 AA; 30680 MW; 99A1F1742C49D87E CRC64;
MLMINSFDNP RLAQAFVDYM ATQGVILEIQ RHDTWDIWLA DEAQAERVKA ELSYFLAHPG
DPRYLSASWQ TGQLNAGLRY RSYPFMASVR AHAGPLTLGM MALCVVAYLA MSIIGSPQVA
VWLAWPFDPS LKFQLWRYVS PLLLHFSLLS LIFNLLWWWY LAGPLERSVG SGKLLTLTLV
TALVGGVIQY QIAGPWFGGL GGVVYALVGY VWLRGEREPE SGLYLPRGIL VFMLLWLAIG
GLGLFGNKTA NADLVAGMLI GLAMAMTDTL HARKRK
