ID   GLPR_PSEAE              Reviewed;         251 AA.
AC   Q51391;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   08-DEC-2000, sequence version 2.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Glycerol-3-phosphate regulon repressor;
GN   Name=glpR; OrderedLocusNames=PA3583;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=8752340; DOI=10.1128/jb.178.17.5215-5221.1996;
RA   Schweizer H.P., Po C.;
RT   "Regulation of glycerol metabolism in Pseudomonas aeruginosa:
RT   characterization of the glpR repressor gene.";
RL   J. Bacteriol. 178:5215-5221(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Repressor of the glycerol-3-phosphate regulon. {ECO:0000250}.
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DR   EMBL; U49666; AAB57805.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG06971.1; -; Genomic_DNA.
DR   PIR; A83197; A83197.
DR   RefSeq; NP_252273.1; NC_002516.2.
DR   RefSeq; WP_003092173.1; NZ_QZGE01000001.1.
DR   AlphaFoldDB; Q51391; -.
DR   SMR; Q51391; -.
DR   STRING; 287.DR97_4356; -.
DR   PaxDb; Q51391; -.
DR   PRIDE; Q51391; -.
DR   DNASU; 880163; -.
DR   EnsemblBacteria; AAG06971; AAG06971; PA3583.
DR   GeneID; 880163; -.
DR   KEGG; pae:PA3583; -.
DR   PATRIC; fig|208964.12.peg.3750; -.
DR   PseudoCAP; PA3583; -.
DR   HOGENOM; CLU_060699_0_0_6; -.
DR   InParanoid; Q51391; -.
DR   OMA; STHEPGF; -.
DR   PhylomeDB; Q51391; -.
DR   BioCyc; PAER208964:G1FZ6-3652-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0010677; P:negative regulation of cellular carbohydrate metabolic process; IMP:PseudoCAP.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR014036; DeoR_C.
DR   InterPro; IPR001034; DeoR_HTH.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00455; DeoRC; 1.
DR   Pfam; PF08220; HTH_DeoR; 1.
DR   PRINTS; PR00037; HTHLACR.
DR   SMART; SM00420; HTH_DEOR; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00894; HTH_DEOR_1; 1.
DR   PROSITE; PS51000; HTH_DEOR_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Glycerol metabolism; Reference proteome; Repressor;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..251
FT                   /note="Glycerol-3-phosphate regulon repressor"
FT                   /id="PRO_0000050254"
FT   DOMAIN          3..58
FT                   /note="HTH deoR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00349"
FT   DNA_BIND        20..39
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00349"
FT   CONFLICT        236
FT                   /note="A -> V (in Ref. 1; AAB57805)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   251 AA;  27568 MW;  79BA63697630428D CRC64;
     MNLPPRQQSI IEEVRERGYL SIEEMAQMFA VTPQTIRRDI NQLAEQGLLR RYHGGAAYDS
     SIENTAYTMR ADQMRDEKQR IAEAVASLVP DNASLFINIG TTTEAIARAL LNHRNLKIIT
     NNLHVAATLS AKEDFEVLVA GGTVRSDGGI VGQAAVDFIQ QFRVDFALVG ISGIDEDGSL
     LDFDYQEVRV SQAIIDNARQ VFLAADSSKF GRNAVVRLGP ISLVNRVISD SPPPAAIARL
     MAQHKVHLDL V