GLR31_ORYSJ
ID GLR31_ORYSJ Reviewed; 938 AA.
AC Q7XP59;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Glutamate receptor 3.1;
DE AltName: Full=Ligand-gated ion channel 3.1;
DE Flags: Precursor;
GN Name=GLR3.1; OrderedLocusNames=Os04g0585200, LOC_Os04g49570;
GN ORFNames=OSJNBa0013K16.8;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBUNIT, TISSUE SPECIFICITY, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=16377757; DOI=10.1105/tpc.105.037713;
RA Li J., Zhu S., Song X., Shen Y., Chen H., Yu J., Yi K., Liu Y.,
RA Karplus V.J., Wu P., Deng X.W.;
RT "A rice glutamate receptor-like gene is critical for the division and
RT survival of individual cells in the root apical meristem.";
RL Plant Cell 18:340-349(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. Involved in root development. May regulate cell
CC proliferation and cell death in the root apex.
CC {ECO:0000269|PubMed:16377757}.
CC -!- SUBUNIT: May form homomultimers. {ECO:0000269|PubMed:16377757}.
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- TISSUE SPECIFICITY: Expressed at low levels in roots and leaves.
CC {ECO:0000269|PubMed:16377757}.
CC -!- INDUCTION: By abiotic stresses.
CC -!- DISRUPTION PHENOTYPE: Plants are defective in root elongation and show
CC reduced mitotic activity and increased cell death in the root apical
CC meristem (RAM). {ECO:0000269|PubMed:16377757}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000305}.
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DR EMBL; DQ305408; ABC33859.1; -; mRNA.
DR EMBL; AL662957; CAE03759.1; -; Genomic_DNA.
DR EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q7XP59; -.
DR SMR; Q7XP59; -.
DR STRING; 4530.OS04T0585200-02; -.
DR PaxDb; Q7XP59; -.
DR PRIDE; Q7XP59; -.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_2_0_1; -.
DR InParanoid; Q7XP59; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; Q7XP59; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR001320; Iontro_rcpt.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
PE 1: Evidence at protein level;
KW Glycoprotein; Ion channel; Ion transport; Ligand-gated ion channel;
KW Membrane; Receptor; Reference proteome; Signal; Stress response;
KW Transmembrane; Transmembrane helix; Transport.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..938
FT /note="Glutamate receptor 3.1"
FT /id="PRO_0000239742"
FT TOPO_DOM 21..588
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 589..609
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 610..618
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 619..639
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 640..650
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 651..671
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 672..830
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 831..851
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 852..938
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 906..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 918..938
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 22
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 39
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 59
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 340
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 418
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 436
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 551
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 938 AA; 103267 MW; 17C0E936D22DF2ED CRC64;
MKFIFYLFSI FCCLCSCAQS QNISGRPDAV RIGAQFARNS TIGRVAAVAV LAAVNDINND
SNILPGTKLD LHMHDSSCNR FLGIVQALQF MEKDTVAIIG PLSSTTAHVL SHLANELHVP
LMSFSATDPT LSSLEYPFFV RTTVSDQFQM TAVADLVEYY GWKQVTTIFV DNDYGRNAIS
SLGDELSKRR SKILYKAPFR PGASNNEIAD VLIKVAMMES RVIILHANPD SGLVVFQQAL
KLGMVSNGYA WIATDWLTSY LDPSVHLDIG LLSTMQGVLT LRHHTENTRR KSMLSSKWSE
LLKEDSGHSR FLLSTYGLYA YDTVWMLAHA LDAFFNSGGN ISFSPDPKLN EISGRGLNLE
ALSVFDGGQL LLEKIHQVDF LGATGPVKFD SGGNLIQPAY DIVSIIGSGL RTVGYWSNYS
GLSVISPETL YKKPANRTRE TQKLHDVIWP GETINKPRGW VFPNNGNEIK IGVPDRVSYR
QFVSVDSETG MVRGLCIDVF VAAINLLAYP VPYRFVPFGN NRENPSYSEL INKIITDDFD
AVVGDVTIIT NRTKVVDFTQ PYVSSGLVVL TSVKRQNSGG WAFLQPFTIK MWTVTGLFFL
IIGTVVWMLE HRINDEFRGP PAKQLITVFW FSFSTLFFAH REDTRSTLGR FVIIIWLFVV
LIIQSSYTAS LTSILTVQQL TSPITGIDSL ITSDVPIGFQ VGSFAENYLA QELGVAHSRL
KALGSPEEYK KALDLGPSKG GVAAIVDERP YIELFLYQNP KFAVVGSEFT KSGWGFAFPR
DSPLSVDLST AILELSENGD LQRIHDKWLA SDMSSMSQAS ELDQDPDRLD VYSFSALFLI
CGLACIFALA IHACNLFYQY SRHAAEEDPA ALQPSASDGS RSLSRRSKLQ SFLSFADRRE
ADIRRAAKEK ASGLGGSGGS MSGVSFTSSG SGSTTASC
