ID   GLRX1_CAMPS             Reviewed;         108 AA.
AC   Q775X4;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Glutaredoxin-1;
GN   OrderedLocusNames=CMP66L;
OS   Camelpox virus (strain CMS).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=203172;
OH   NCBI_TaxID=9836; Camelus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11907336; DOI=10.1099/0022-1317-83-4-855;
RA   Gubser C., Smith G.L.;
RT   "The sequence of camelpox virus shows it is most closely related to variola
RT   virus, the cause of smallpox.";
RL   J. Gen. Virol. 83:855-872(2002).
CC   -!- FUNCTION: Has thioltransferase and dehydroascorbate reductase
CC       activities. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion. Note=Localizes to the virion core.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glutaredoxin family. {ECO:0000305}.
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DR   EMBL; AY009089; AAG37534.1; -; Genomic_DNA.
DR   SMR; Q775X4; -.
DR   Proteomes; UP000107153; Genome.
DR   GO; GO:0097573; F:glutathione oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0004362; F:glutathione-disulfide reductase (NADPH) activity; IEA:InterPro.
DR   InterPro; IPR011767; GLR_AS.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR011899; Glutaredoxin_euk/vir.
DR   InterPro; IPR014025; Glutaredoxin_subgr.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   PRINTS; PR00160; GLUTAREDOXIN.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02180; GRX_euk; 1.
DR   PROSITE; PS00195; GLUTAREDOXIN_1; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Electron transport; Redox-active center; Transport; Virion.
FT   CHAIN           1..108
FT                   /note="Glutaredoxin-1"
FT                   /id="PRO_0000141621"
FT   DOMAIN          3..106
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   DISULFID        23..26
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   108 AA;  12357 MW;  826BBB0A63905519 CRC64;
     MAEEFVQQRL ANNKVTIFVK FTCPFCRNAL DILNKFSFKR GAYEIVDIKE FKPENELRDY
     FEQITGGRTV PRIFFGKTSI GGYSDMLEID NMDALGDILS SIGVLRTC