ID   GLRX_VERFO              Reviewed;         104 AA.
AC   O81187;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Glutaredoxin;
OS   Vernicia fordii (Tung) (Aleurites fordii).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Aleuritideae;
OC   Vernicia.
OX   NCBI_TaxID=73154;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. L-2; TISSUE=Seed;
RA   Tang F., Dyer J.M., Lax A.R., Shih D.S., Chapital D.C., Pepperman A.B.;
RT   "Nucleotide sequence of a cDNA clone for glutaredoxin from Aleurites fordii
RT   seeds.";
RL   (er) Plant Gene Register PGR98-090(1998).
CC   -!- FUNCTION: Has a glutathione-disulfide oxidoreductase activity in the
CC       presence of NADPH and glutathione reductase. Reduces low molecular
CC       weight disulfides and proteins (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glutaredoxin family. CPYC subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AF047694; AAC39481.1; -; mRNA.
DR   AlphaFoldDB; O81187; -.
DR   SMR; O81187; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097573; F:glutathione oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0004362; F:glutathione-disulfide reductase (NADPH) activity; IEA:InterPro.
DR   InterPro; IPR011767; GLR_AS.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR011899; Glutaredoxin_euk/vir.
DR   InterPro; IPR014025; Glutaredoxin_subgr.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   PRINTS; PR00160; GLUTAREDOXIN.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02180; GRX_euk; 1.
DR   PROSITE; PS00195; GLUTAREDOXIN_1; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Disulfide bond; Electron transport; Redox-active center;
KW   Transport.
FT   CHAIN           1..104
FT                   /note="Glutaredoxin"
FT                   /id="PRO_0000141609"
FT   DOMAIN          3..103
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   DISULFID        23..26
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   104 AA;  11128 MW;  9F5FC7E99D4362BD CRC64;
     MAMIKAQELV SSNSVVVFSK TFCPYCTSVK QLLNQLGAQF KVIELDSESD GSDLQNALAE
     WTGQRTVPNV FIGGKHIGGC DKTTGMHQEG KLIPLLTEAG AVKA