ID   AMID_STRPN              Reviewed;         308 AA.
AC   P0A4M9; P18794;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Oligopeptide transport system permease protein AmiD;
GN   Name=amiD; OrderedLocusNames=SP_1889;
OS   Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=170187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=R6 / R800;
RX   PubMed=2352474; DOI=10.1111/j.1365-2958.1990.tb00632.x;
RA   Alloing G., Trombe M.C., Claverys J.-P.;
RT   "The ami locus of the Gram-positive bacterium Streptococcus pneumoniae is
RT   similar to binding protein-dependent transport operons of Gram-negative
RT   bacteria.";
RL   Mol. Microbiol. 4:633-644(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-334 / TIGR4;
RX   PubMed=11463916; DOI=10.1126/science.1061217;
RA   Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA   Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA   Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA   Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA   Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA   McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA   Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA   Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT   "Complete genome sequence of a virulent isolate of Streptococcus
RT   pneumoniae.";
RL   Science 293:498-506(2001).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       oligopeptides; probably responsible for the translocation of the
CC       substrate across the membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. OppBC subfamily. {ECO:0000305}.
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DR   EMBL; X17337; CAA35215.1; -; Genomic_DNA.
DR   EMBL; AE005672; AAK75960.1; -; Genomic_DNA.
DR   PIR; G95220; G95220.
DR   PIR; S11151; S11151.
DR   RefSeq; WP_000103700.1; NZ_AKVY01000001.1.
DR   AlphaFoldDB; P0A4M9; -.
DR   STRING; 170187.SP_1889; -.
DR   EnsemblBacteria; AAK75960; AAK75960; SP_1889.
DR   GeneID; 60232445; -.
DR   GeneID; 66806961; -.
DR   KEGG; spn:SP_1889; -.
DR   eggNOG; COG1173; Bacteria.
DR   OMA; IGFNYIF; -.
DR   PhylomeDB; P0A4M9; -.
DR   BioCyc; SPNE170187:G1FZB-1919-MON; -.
DR   Proteomes; UP000000585; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR025966; OppC_N.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   Pfam; PF12911; OppC_N; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Peptide transport; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..308
FT                   /note="Oligopeptide transport system permease protein AmiD"
FT                   /id="PRO_0000059945"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        145..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        171..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          107..295
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   308 AA;  34635 MW;  EDE6383D284FE7C0 CRC64;
     MSTIDKEKFQ FVKRDDFASE TIDAPAYSYW KSVFKQFMKK KSTVVMLGIL VAIILISFIY
     PMFSKFDFND VSKVNDFSVR YIKPNAEHWF GTDSNGKSLF DGVWFGARNS ILISVIATVI
     NLVIGVFVGG IWGISKSVDR VMMEVYNVIS NIPPLLIVIV LTYSIGAGFW NLIFAMSVTT
     WIGIAFMIRV QILRYRDLEY NLASRTLGTP TLKIVAKNIM PQLVSVIVTT MTQMLPSFIS
     YEAFLSFFGL GLPITVPSLG RLISDYSQNV TTNAYLFWIP LTTLVLVSLS LFVVGQNLAD
     ASDPRTHR