ID   GLST_MYCBP              Reviewed;         327 AA.
AC   A1KIG2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Glycolipid sulfotransferase BCG_1434;
DE            EC=2.8.2.-;
GN   OrderedLocusNames=BCG_1434;
OS   Mycobacterium bovis (strain BCG / Pasteur 1173P2).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=410289;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCG / Pasteur 1173P2;
RX   PubMed=17372194; DOI=10.1073/pnas.0700869104;
RA   Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P.,
RA   Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K.,
RA   Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C.,
RA   Barrell B.G., Parkhill J., Cole S.T.;
RT   "Genome plasticity of BCG and impact on vaccine efficacy.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007).
CC   -!- FUNCTION: Involved in the synthesis of cell wall sulfolipids.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the sulfotransferase 1 family. {ECO:0000305}.
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DR   EMBL; AM408590; CAL71421.1; -; Genomic_DNA.
DR   AlphaFoldDB; A1KIG2; -.
DR   SMR; A1KIG2; -.
DR   KEGG; mbb:BCG_1434; -.
DR   HOGENOM; CLU_027239_3_0_11; -.
DR   OMA; HANLNRR; -.
DR   Proteomes; UP000001472; Chromosome.
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   Transferase.
FT   CHAIN           1..327
FT                   /note="Glycolipid sulfotransferase BCG_1434"
FT                   /id="PRO_0000315391"
FT   ACT_SITE        97
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255"
FT   BINDING         40..45
FT                   /ligand="3'-phosphoadenylyl sulfate"
FT                   /ligand_id="ChEBI:CHEBI:58339"
FT                   /evidence="ECO:0000250"
FT   BINDING         116..124
FT                   /ligand="3'-phosphoadenylyl sulfate"
FT                   /ligand_id="ChEBI:CHEBI:58339"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   327 AA;  37119 MW;  96FD2B7425F39302 CRC64;
     MNSEHPMTDR VVYRSLMADN LRWDALQLRD GDIIISAPSK SGLTWTQRLV SLLVFDGPDL
     PGPLSTVSPW LDQTIRPIEE VVATLDAQQH RRFIKTHTPL DGLVLDDRVS YICVGRDPRD
     AAVSMLYQSA NMNEDRMRIL HEAVVPFHER IAPPPFAELG HARSPTEEFR DWMEGPNQPP
     PGIGFTHLKG IGTLANILHQ LGTVWVRRHL PNVALFHYAD YQADLAGELL RLARVLGIAA
     TRDRARDLAQ YATLDAMRSR ASEIAPNTTD GIWHSDERFF RRGGSGDWQQ FFTEAEHLRY
     YHRINQLAPP DLLAWAHEGR RGYDPAN