GLT2_ARATH
ID GLT2_ARATH Reviewed; 220 AA.
AC Q9LMC9;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Germin-like protein subfamily T member 2;
DE Flags: Precursor;
GN OrderedLocusNames=At1g18980; ORFNames=F14D16.13, F14D16_8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in plant defense. Probably has no oxalate
CC oxidase activity even if the active site is conserved.
CC -!- SUBUNIT: Oligomer (believed to be a pentamer but probably hexamer).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the germin family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC068602; AAF79303.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29786.1; -; Genomic_DNA.
DR EMBL; AY084870; AAM61433.1; -; mRNA.
DR PIR; F86323; F86323.
DR RefSeq; NP_173332.1; NM_101755.3.
DR AlphaFoldDB; Q9LMC9; -.
DR SMR; Q9LMC9; -.
DR STRING; 3702.AT1G18980.1; -.
DR PaxDb; Q9LMC9; -.
DR PRIDE; Q9LMC9; -.
DR ProteomicsDB; 248527; -.
DR EnsemblPlants; AT1G18980.1; AT1G18980.1; AT1G18980.
DR GeneID; 838479; -.
DR Gramene; AT1G18980.1; AT1G18980.1; AT1G18980.
DR KEGG; ath:AT1G18980; -.
DR Araport; AT1G18980; -.
DR TAIR; locus:2011306; AT1G18980.
DR eggNOG; ENOG502QSRM; Eukaryota.
DR HOGENOM; CLU_015790_0_3_1; -.
DR InParanoid; Q9LMC9; -.
DR OMA; SAGQMFV; -.
DR OrthoDB; 1164277at2759; -.
DR PhylomeDB; Q9LMC9; -.
DR PRO; PR:Q9LMC9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LMC9; baseline and differential.
DR Genevisible; Q9LMC9; AT.
DR GO; GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR Gene3D; 2.60.120.10; -; 1.
DR InterPro; IPR006045; Cupin_1.
DR InterPro; IPR001929; Germin.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR Pfam; PF00190; Cupin_1; 1.
DR PRINTS; PR00325; GERMIN.
DR SMART; SM00835; Cupin_1; 1.
DR SUPFAM; SSF51182; SSF51182; 1.
PE 2: Evidence at transcript level;
KW Apoplast; Disulfide bond; Glycoprotein; Manganese; Metal-binding;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..220
FT /note="Germin-like protein subfamily T member 2"
FT /id="PRO_0000010831"
FT DOMAIN 64..212
FT /note="Cupin type-1"
FT /evidence="ECO:0000255"
FT BINDING 112
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 114
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 119
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 158
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT CARBOHYD 71
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 136
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 37..52
FT /evidence="ECO:0000250"
SQ SEQUENCE 220 AA; 23184 MW; E9E5A32CB81CAD25 CRC64;
MTTLQISSSL FRSFLLVICV FVIPSLSSDS DPLQDFCVGD LKASPSINGF PCKSSVSASD
FFFSGLGGPL NTSTPNGVAV SPANVLTFPG LNTLGLSMNN VEFAPGGVNP PHSHPRATEA
GVVIEGSVFV GFLTTNNTLF SKVLNAGEMF VVPRGLVHFQ WNVGKVKARL ITSFNSQLPG
SAVLPSTLFG SNPTIPNAVL TKTFRTDDVT VNKLKSKFAV
