GLT3_WHEAT
ID GLT3_WHEAT Reviewed; 660 AA.
AC P08488;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1988, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Glutenin, high molecular weight subunit 12;
DE Flags: Precursor;
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Chinese Spring;
RX PubMed=3840588; DOI=10.1093/nar/13.19.6833;
RA Thompson R.D., Bartels D., Harberd N.P.;
RT "Nucleotide sequence of a gene from chromosome 1D of wheat encoding a HMW-
RT glutenin subunit.";
RL Nucleic Acids Res. 13:6833-6846(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 126-660.
RX PubMed=2597130; DOI=10.1042/bj2630837;
RA Goldsbrough A.P., Bulleid N.J., Freedman R.B., Flavell R.B.;
RT "Conformational differences between two wheat (Triticum aestivum) 'high-
RT molecular-weight' glutenin subunits are due to a short region containing
RT six amino acid differences.";
RL Biochem. J. 263:837-842(1989).
CC -!- FUNCTION: Glutenins are high-molecular weight seed storage proteins of
CC wheat endosperm. Thought to be responsible for the visco-elastic
CC property of wheat dough.
CC -!- SUBUNIT: Disulfide-bridge linked aggregates.
CC -!- MISCELLANEOUS: Glutenins are coded by several genes on each of the
CC group 1 chromosomes of wheat.
CC -!- MISCELLANEOUS: The mature protein is characterized by a large number of
CC well preserved repeats of the two motifs: GQQPGQ and GQQPGQGQQGYYPTS.
CC -!- SIMILARITY: Belongs to the gliadin/glutenin family. {ECO:0000305}.
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DR EMBL; X03041; CAA26847.1; -; Genomic_DNA.
DR PIR; A24266; A24266.
DR AlphaFoldDB; P08488; -.
DR SMR; P08488; -.
DR Allergome; 2898; Tri a 26.
DR PRIDE; P08488; -.
DR Proteomes; UP000019116; Unplaced.
DR GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR CDD; cd00261; AAI_SS; 1.
DR Gene3D; 1.10.110.10; -; 1.
DR InterPro; IPR044723; AAI_SS_dom.
DR InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR InterPro; IPR001419; Glutenin.
DR Pfam; PF03157; Glutenin_hmw; 4.
DR PRINTS; PR00210; GLUTENIN.
DR SUPFAM; SSF47699; SSF47699; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Reference proteome; Repeat; Seed storage protein; Signal;
KW Storage protein.
FT SIGNAL 1..21
FT CHAIN 22..660
FT /note="Glutenin, high molecular weight subunit 12"
FT /id="PRO_0000032208"
FT REGION 127..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..645
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 660 AA; 70867 MW; 2BFD09D8C8FCCCFF CRC64;
MAKRLVLFAA VVIALVALTT AEGEASRQLQ CERELQESSL EACRQVVDQQ LAGRLPWSTG
LQMRCCQQLR DVSAKCRSVA VSQVARQYEQ TVVPPKGGSF YPGETTPLQQ LQQGIFWGTS
SQTVQGYYPS VTSPRQGSYY PGQASPQQPG QGQQPGKWQE PGQGQQWYYP TSLQQPGQGQ
QIGKGKQGYY PTSLQQPGQG QQIGQGQQGY YPTSPQHTGQ RQQPVQGQQI GQGQQPEQGQ
QPGQWQQGYY PTSPQQLGQG QQPGQWQQSG QGQQGHYPTS LQQPGQGQQG HYLASQQQPA
QGQQGHYPAS QQQPGQGQQG HYPASQQQPG QGQQGHYPAS QQEPGQGQQG QIPASQQQPG
QGQQGHYPAS LQQPGQQGHY PTSLQQLGQG QQIGQPGQKQ QPGQGQQTGQ GQQPEQEQQP
GQGQQGYYPT SLQQPGQGQQ QGQGQQGYYP TSLQQPGQGQ QGHYPASLQQ PGQGQGQPGQ
RQQPGQGQHP EQGQQPGQGQ QGYYPTSPQQ PGQGQQLGQG QQGYYPTSPQ QPGQGQQPGQ
GQQGHCPMSP QQTGQAQQLG QGQQIGQVQQ PGQGQQGYYP TSLQQPGQGQ QSGQGQQSGQ
GHQPGQGQQS GQEKQGYDSP YHVSAEQQAA SPMVAKAQQP ATQLPTVCRM EGGDALSASQ
