ID   GLT4_WHEAT              Reviewed;         838 AA.
AC   P08489;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Glutenin, high molecular weight subunit PW212;
DE   Flags: Precursor;
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Yamhill;
RX   PubMed=3001648; DOI=10.1093/nar/13.24.8729;
RA   Sugiyama T., Rafalski A., Peterson D., Soll D.G.;
RT   "A wheat HMW glutenin subunit gene reveals a highly repeated structure.";
RL   Nucleic Acids Res. 13:8729-8737(1985).
CC   -!- FUNCTION: Glutenins are high-molecular weight seed storage proteins of
CC       wheat endosperm. Thought to be responsible for the visco-elastic
CC       property of wheat dough.
CC   -!- SUBUNIT: Disulfide-bridge linked aggregates.
CC   -!- MISCELLANEOUS: Glutenins are coded by several genes on each of the
CC       group 1 chromosomes of wheat.
CC   -!- MISCELLANEOUS: The mature protein is characterized by a large number of
CC       well preserved repeats of the two motifs: GQQPGQ and GQQPGQGQQGYYPTS.
CC   -!- SIMILARITY: Belongs to the gliadin/glutenin family. {ECO:0000305}.
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DR   EMBL; X03346; CAA27052.1; -; Genomic_DNA.
DR   PIR; A24107; EEWTHW.
DR   AlphaFoldDB; P08489; -.
DR   Allergome; 2898; Tri a 26.
DR   PRIDE; P08489; -.
DR   Proteomes; UP000019116; Unplaced.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   InterPro; IPR001419; Glutenin.
DR   Pfam; PF03157; Glutenin_hmw; 2.
DR   PRINTS; PR00210; GLUTENIN.
DR   SUPFAM; SSF47699; SSF47699; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Reference proteome; Repeat; Seed storage protein; Signal;
KW   Storage protein.
FT   SIGNAL          1..21
FT   CHAIN           22..838
FT                   /note="Glutenin, high molecular weight subunit PW212"
FT                   /id="PRO_0000032209"
FT   REGION          122..794
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   838 AA;  89173 MW;  71D715B7BDF0722D CRC64;
     MAKRLVLFVA VVVALVALTV AEGEASEQLQ CERELQELQE RELKACQQVM DQQLRDISPE
     CHPVVVSPVA GQYEQQIVVP KGGSFYPGET TPPQQLQQRI FWGIPALLKR YYPSVTSPQQ
     VSYYPGQASP QRPGQGQQPG QGQQSGQGQQ GYYPTSPQQP GQWQQPEQGQ PGYYPTSPQQ
     PGQLQQPAQG QQPGQGQQGR QPGQGQPGYY PTSSQLQPGQ LQQPAQGQQG QQPGQGQQGQ
     QPGQGQQPGQ GQQGQQPGQG QQPGQGQQGQ QLGQGQQGYY PTSLQQSGQG QPGYYPTSLQ
     QLGQGQSGYY PTSPQQPGQG QQPGQLQQPA QGQQPEQGQQ GQQPGQGQQG QQPGQGQQPG
     QGQPGYYPTS PQQSGQGQPG YYPTSSQQPT QSQQPGQGQQ GQQVGQGQQA QQPGQGQQPG
     QGQPGYYPTS PLQSGQGQPG YYLTSPQQSG QGQQPGQLQQ SAQGQKGQQP GQGQQPGQGQ
     QGQQPGQGQQ GQQPGQGQPG YYPTSPQQSG QGQQPGQWQQ PGQGQPGYYP TSPLQPGQGQ
     PGYDPTSPQQ PGQGQQPGQL QQPAQGQQGQ QLAQGQQGQQ PAQVQQGQQP AQGQQGQQLG
     QGQQGQQPGQ GQQPAQGQQG QQPGQGQQGQ QPGQGQQPGQ GQPWYYPTSP QESGQGQQPG
     QWQQPGQWQQ PGQGQPGYYL TSPLQLGQGQ QGYYPTSLQQ PGQGQQPGQW QQSGQGQHGY
     YPTSPQLSGQ GQRPGQWLQP GQGQQGYYPT SPQQSGQGQQ LGQWLQPGQG QQGYYPTSLQ
     QTGQGQQSGQ GQQGYYSSYH VSVEHQAASL KVAKAQQLAA QLPAMCRLEG GDALSASQ